中国保健营养(中旬刊)
中國保健營養(中旬刊)
중국보건영양(중순간)
China Hwalth Care & nutrition
2013年
4期
1-2
,共2页
谢莉敏%李丹%程秀芳%刘虹%黄启亮%王丛丛%谷巍
謝莉敏%李丹%程秀芳%劉虹%黃啟亮%王叢叢%穀巍
사리민%리단%정수방%류홍%황계량%왕총총%곡외
氨苄西林钠%肠道菌群%模型
氨芐西林鈉%腸道菌群%模型
안변서림납%장도균군%모형
Ampicillin Na%Intestinal Flora%Effection%Model
目的:研究氨苄西林钠对小鼠肠道菌群的影响,为科学研究正确使用氨苄西林钠提供参考资料;方法:以22.4g/kg剂量的氨苄西林钠连续灌胃小鼠3d,5d,分别于停药后第1d,3d,7d,10d和第15d检测小鼠直肠球菌、杆菌、乳酸菌及双歧杆菌数;结果:各氨苄西林钠给药组皆可造成小鼠肠道菌群失调,长时间灌胃组小鼠难以恢复;结论:以22.4g/kg剂量的头孢氨苄青霉素灌胃3d可用于制备肠道菌群失调模型。
目的:研究氨芐西林鈉對小鼠腸道菌群的影響,為科學研究正確使用氨芐西林鈉提供參攷資料;方法:以22.4g/kg劑量的氨芐西林鈉連續灌胃小鼠3d,5d,分彆于停藥後第1d,3d,7d,10d和第15d檢測小鼠直腸毬菌、桿菌、乳痠菌及雙歧桿菌數;結果:各氨芐西林鈉給藥組皆可造成小鼠腸道菌群失調,長時間灌胃組小鼠難以恢複;結論:以22.4g/kg劑量的頭孢氨芐青黴素灌胃3d可用于製備腸道菌群失調模型。
목적:연구안변서림납대소서장도균군적영향,위과학연구정학사용안변서림납제공삼고자료;방법:이22.4g/kg제량적안변서림납련속관위소서3d,5d,분별우정약후제1d,3d,7d,10d화제15d검측소서직장구균、간균、유산균급쌍기간균수;결과:각안변서림납급약조개가조성소서장도균군실조,장시간관위조소서난이회복;결론:이22.4g/kg제량적두포안변청매소관위3d가용우제비장도균군실조모형。
Objective:Through observing the effection of Ampicillin Na on the intestinal flora of mice,so as to provide the reference data for the correct use of Ampicillin Na on the study work.Methods:The mice in study groups were continuous lavaged 22.4g/kg doses of Ampicillin Na 3days and 5days,then test the number of bacillus,enterococci,lactobacillus and bifidobacterium in rectal of mice after stop giving Ampicillin Na 1,3,7,10,15th days. Results:The Ampicillin Na treatment groups all can cause mice intestinal dysbacteriosis,and longer group difficult to get well .Conclusion:Giving mice 22.4g/kg doses Ampicillin Na can be used in the preparation of mice intestinal dysbacteriosis model.