微循环学杂志
微循環學雜誌
미순배학잡지
CHINESE JOURNAL OF MICROCIRCULATION
2014年
2期
38-41
,共4页
慢性阻塞性肺疾病%高黏血症%中西医结合治疗
慢性阻塞性肺疾病%高黏血癥%中西醫結閤治療
만성조새성폐질병%고점혈증%중서의결합치료
Chronic obstructive pulmonary disease%Blood hyperviscosity%Combination treatment of traditional Chi-nese medicine and western medicine
目的：观察银杏达莫注射液联合内服外敷中药治疗慢性阻塞性肺疾病(简称慢阻肺,COPD)合并高黏血症的临床疗效。方法：88例COPD合并高黏血症患者分为治疗组(n=44)与对照组(n=44),对照组给予西医常规治疗,治疗组在对照组治疗的基础上,给予静脉滴注银杏达莫注射液,并予以中药内服和穴位贴敷。14天后观察两组临床疗效及血液流变学指标变化。结果：连续治疗14天后,治疗组临床痊愈率明显高于对照组(45.45%vs25.00%,P<0.05),无效率显著低于对照组(6.82%vs22.73%,P<0.05)。治疗组高切表观黏度、低切表观黏度、红细胞压积、血浆黏度、血浆纤维蛋白原含量和红细胞聚集指数等指标均较治疗前明显改善(P<0.01)；治疗组与对照组治疗后比较,除红细胞聚集指数外,其它指标均显著降低,差异有统计学意义(P<0.05)。结论：银杏达莫注射液联合内服外敷中药治疗COPD合并高黏血症,可明显提高临床痊愈率并显著改善血液流变状态。
目的：觀察銀杏達莫註射液聯閤內服外敷中藥治療慢性阻塞性肺疾病(簡稱慢阻肺,COPD)閤併高黏血癥的臨床療效。方法：88例COPD閤併高黏血癥患者分為治療組(n=44)與對照組(n=44),對照組給予西醫常規治療,治療組在對照組治療的基礎上,給予靜脈滴註銀杏達莫註射液,併予以中藥內服和穴位貼敷。14天後觀察兩組臨床療效及血液流變學指標變化。結果：連續治療14天後,治療組臨床痊愈率明顯高于對照組(45.45%vs25.00%,P<0.05),無效率顯著低于對照組(6.82%vs22.73%,P<0.05)。治療組高切錶觀黏度、低切錶觀黏度、紅細胞壓積、血漿黏度、血漿纖維蛋白原含量和紅細胞聚集指數等指標均較治療前明顯改善(P<0.01)；治療組與對照組治療後比較,除紅細胞聚集指數外,其它指標均顯著降低,差異有統計學意義(P<0.05)。結論：銀杏達莫註射液聯閤內服外敷中藥治療COPD閤併高黏血癥,可明顯提高臨床痊愈率併顯著改善血液流變狀態。
목적：관찰은행체막주사액연합내복외부중약치료만성조새성폐질병(간칭만조폐,COPD)합병고점혈증적림상료효。방법：88례COPD합병고점혈증환자분위치료조(n=44)여대조조(n=44),대조조급여서의상규치료,치료조재대조조치료적기출상,급여정맥적주은행체막주사액,병여이중약내복화혈위첩부。14천후관찰량조림상료효급혈액류변학지표변화。결과：련속치료14천후,치료조림상전유솔명현고우대조조(45.45%vs25.00%,P<0.05),무효솔현저저우대조조(6.82%vs22.73%,P<0.05)。치료조고절표관점도、저절표관점도、홍세포압적、혈장점도、혈장섬유단백원함량화홍세포취집지수등지표균교치료전명현개선(P<0.01)；치료조여대조조치료후비교,제홍세포취집지수외,기타지표균현저강저,차이유통계학의의(P<0.05)。결론：은행체막주사액연합내복외부중약치료COPD합병고점혈증,가명현제고림상전유솔병현저개선혈액류변상태。
Objective:To analyze the clinical effect of injecting Ginkgo leaf extract and dipyridamole,together with internal and external treatment of traditional Chinese medicine in chronic obstructive pulmonary disease (COPD)combined with blood hyperviscosity.Method:Eighty-eight cases of COPD combined with blood hyperviscosity were divided in-to the intervention group (n=44)and the control group (n=44).The control group received conventional western medication treatment.And the intervention group received inj ecting Ginkgo leaf extract and dipyridamole,and inter-nal/external treatment of traditional Chinese medicine on the basis of the conventional medication.After 14 days, clinical effects and hemodynamic changes were compared between two groups.Results:14 days after treatment,the cure rate in the intervention group was significantly higher than that in the control group (45.45% vs 25.00%,re-spectively,P<0.05).The inefficiency rate in the intervention group was significantly lower than that in the control group (6.82% vs 22.73%,respectively,P<0.05).Within the intervention group,the indices of blood rheology , including high viscosity,low shear viscosity,hematocrit,plasma viscosity,fibrinogen and erythrocyte aggregation index,were significantly improved after treatment (P<0.01).All the indices of blood rheology after treatment in the intervention group,except the red cell aggregation index,decreased significantly compared with the control group (P<0.05).Conclusion:Injecting Ginkgo leaf extract and dipyridamole,together with internal and external treatment of traditional Chinese medicine in the treatment of high blood viscosity with COPD can significantly im-prove the clinical cure rate and the state of blood rheology.
