CAJ | 학술논문

目的：观察荆花胃康胶丸联合盐酸伊托必利分散片治疗功能性消化不良（ FD）的临床疗效。方法将158例FD患者随机分为2组。治疗组79例予荆花胃康胶丸联合盐酸伊托必利分散片治疗，对照组79例仅予盐酸伊托必利分散片治疗，2组疗程均为4周。比较2组疗效，观察2组治疗前后主要临床症状评分变化。结果治疗组总有效率92．41％，对照组总有效率60．76％，2组总有效率比较差异有统计学意义（P＜0．05），治疗组疗效优于对照组。2组治疗后主要临床症状评分均较本组治疗前降低（P＜0．05），且治疗组降低明显（P＜0．05）。结论荆花胃康胶丸联合盐酸伊托必利分散片治疗FD，可明显提高疗效，不良反应无明显增加。
목적：관찰형화위강효환연합염산이탁필리분산편치료공능성소화불량（ FD）적림상료효。방법장158례FD환자수궤분위2조。치료조79례여형화위강효환연합염산이탁필리분산편치료，대조조79례부여염산이탁필리분산편치료，2조료정균위4주。비교2조료효，관찰2조치료전후주요림상증상평분변화。결과치료조총유효솔92．41％，대조조총유효솔60．76％，2조총유효솔비교차이유통계학의의（P＜0．05），치료조료효우우대조조。2조치료후주요림상증상평분균교본조치료전강저（P＜0．05），차치료조강저명현（P＜0．05）。결론형화위강효환연합염산이탁필리분산편치료FD，가명현제고료효，불량반응무명현증가。
Objective To study the efficacy of combined therapy of Jinghuaweikang capsule and Itopride hydrochloride dispersible tablets for functional dyspepsia .Methods One hundred and fifty eight patients with func-tional dyspepsia were randomly grouped into experimental group ( n=79 ) and the control group ( n=79 ) .The pa-tients in the experimental group were given 2 capsule of Jinghuaweikang capsule ,3 times a day in addition to Itopride Hydrochloride Tablets 50 mg,3 times per day for four weeks .The patients in the control group were only given Itopride Hydrochloride Tablets 3 times a day for 4 weeks.The therapeutic efficacy and side effects were compared between the two groups by chi square test .Results The total effective rate in the experimental group (92.41%) was superior to that in the control group (60.76%,P<0.05).No severe side-effects were found in the both groups .Conclusion Jinghuaweikang capsules combined with Itopride hydrochloride dispersible tablets can more significantly improve gen -eral efficacy and symptoms in patients with functional dyspepsia than single use of motility medicine Itopride hydro -chloride dispersible tablets .