化工技术与开发
化工技術與開髮
화공기술여개발
TECHNOLOGY & DVELOPMENT OF CHEMICAL INDUSTRY
2014年
2期
20-24
,共5页
白芷香豆素%乙醇提取%单因素实验%响应面优化
白芷香豆素%乙醇提取%單因素實驗%響應麵優化
백지향두소%을순제취%단인소실험%향응면우화
angelica dahurica%ethanol extraction%single factor experiment%optimization by response surface methodology
采用响应面法优化并确定白芷总香豆素的乙醇提取工艺。利用单因素试验方法，以白芷总香豆素的含量作为评价指标，研究乙醇浓度、乙醇用量、提取时间对白芷总香豆素提取量的影响，同时利用Design-Expert 8.0.7.1响应面分析统计学方法构造模型，优化并确定白芷总香豆素的乙醇提取工艺。确定白芷总香豆素乙醇提取工艺的最优提取条件为：提取时间为4.23h，乙醇浓度为62.1%，固液比为1∶382。通过实验结果对模型进行验证，实验值与理论值的相对误差为0.60%，说明模型可靠性高，可作为白芷工业化规模提取的工艺借鉴。
採用響應麵法優化併確定白芷總香豆素的乙醇提取工藝。利用單因素試驗方法，以白芷總香豆素的含量作為評價指標，研究乙醇濃度、乙醇用量、提取時間對白芷總香豆素提取量的影響，同時利用Design-Expert 8.0.7.1響應麵分析統計學方法構造模型，優化併確定白芷總香豆素的乙醇提取工藝。確定白芷總香豆素乙醇提取工藝的最優提取條件為：提取時間為4.23h，乙醇濃度為62.1%，固液比為1∶382。通過實驗結果對模型進行驗證，實驗值與理論值的相對誤差為0.60%，說明模型可靠性高，可作為白芷工業化規模提取的工藝藉鑒。
채용향응면법우화병학정백지총향두소적을순제취공예。이용단인소시험방법，이백지총향두소적함량작위평개지표，연구을순농도、을순용량、제취시간대백지총향두소제취량적영향，동시이용Design-Expert 8.0.7.1향응면분석통계학방법구조모형，우화병학정백지총향두소적을순제취공예。학정백지총향두소을순제취공예적최우제취조건위：제취시간위4.23h，을순농도위62.1%，고액비위1∶382。통과실험결과대모형진행험증，실험치여이론치적상대오차위0.60%，설명모형가고성고，가작위백지공업화규모제취적공예차감。
The total coumarin angelica ethanol extraction process was optimized and obtained by response surface methodology. Using single factor test method, angelica total content of coumarin as the evaluation index, the ethanol concentration and ethanol, extraction time on the extraction of angelica total amount of coumarin were studied. Design-Expert 8.0.7.1 response surface analysis of statistical method was used to construct the model, optimize and determine the total coumarin angelica ethanol extraction process. The total coumarin ethanol extraction process angelica optimal extraction conditions were: extraction time of optimum conditions 4.23h, ethanol concentration was 62.1%, solid-liquid ratio of 1:382. The results validated the model, experimental and theoretical values of the relative error of 0.60%, indicated that the model high reliability could be used as industrial-scale extraction process Angelica reference.
