中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
11期
1620-1621
,共2页
2型糖尿病%神经%膀胱%α-硫辛酸%莫沙必利
2型糖尿病%神經%膀胱%α-硫辛痠%莫沙必利
2형당뇨병%신경%방광%α-류신산%막사필리
Type 2 diabetes%Nerve%Urinary bladder%Lipoic acid%Mosapride
目的 观察α-硫辛酸、莫沙必利联合治疗糖尿病神经源性膀胱的临床疗效.方法 30例2型糖尿病神经源性膀胱患者,在良好控制血糖、血脂等代谢指标的基础上,给α-硫辛酸、莫沙必利联合治疗3周,比较治疗前后膀胱残余尿量及尿动力学指标的变化.结果 治疗3周及停药4周后患者膀胱残余尿量、平均尿流率、最大尿流率、逼尿肌压力分别为(62.5±27.8) ml和(61.3±21.6) ml、(8.3±1.9) ml/s和(7.9±2.1)ml/s、(10.7±1.8) ml/s和(10.3±1.6) ml/s、(25.6±2.7)cm H2O和(24.5 ±2.3)cm H2O,均优于治疗前的(128.3 ±72.5) ml、(5.2±1.3)ml/s、(8.4±1.2) ml/s、(18.1±1.2)cm H2O(t =4.01、4.21、3.45、3.52、3.68、3.47、3.33、3.24,均P＜0.01).结论 α-硫辛酸联合莫沙必利治疗糖尿病神经源性膀胱有较好的临床疗效.
目的 觀察α-硫辛痠、莫沙必利聯閤治療糖尿病神經源性膀胱的臨床療效.方法 30例2型糖尿病神經源性膀胱患者,在良好控製血糖、血脂等代謝指標的基礎上,給α-硫辛痠、莫沙必利聯閤治療3週,比較治療前後膀胱殘餘尿量及尿動力學指標的變化.結果 治療3週及停藥4週後患者膀胱殘餘尿量、平均尿流率、最大尿流率、逼尿肌壓力分彆為(62.5±27.8) ml和(61.3±21.6) ml、(8.3±1.9) ml/s和(7.9±2.1)ml/s、(10.7±1.8) ml/s和(10.3±1.6) ml/s、(25.6±2.7)cm H2O和(24.5 ±2.3)cm H2O,均優于治療前的(128.3 ±72.5) ml、(5.2±1.3)ml/s、(8.4±1.2) ml/s、(18.1±1.2)cm H2O(t =4.01、4.21、3.45、3.52、3.68、3.47、3.33、3.24,均P＜0.01).結論 α-硫辛痠聯閤莫沙必利治療糖尿病神經源性膀胱有較好的臨床療效.
목적 관찰α-류신산、막사필리연합치료당뇨병신경원성방광적림상료효.방법 30례2형당뇨병신경원성방광환자,재량호공제혈당、혈지등대사지표적기출상,급α-류신산、막사필리연합치료3주,비교치료전후방광잔여뇨량급뇨동역학지표적변화.결과 치료3주급정약4주후환자방광잔여뇨량、평균뇨류솔、최대뇨류솔、핍뇨기압력분별위(62.5±27.8) ml화(61.3±21.6) ml、(8.3±1.9) ml/s화(7.9±2.1)ml/s、(10.7±1.8) ml/s화(10.3±1.6) ml/s、(25.6±2.7)cm H2O화(24.5 ±2.3)cm H2O,균우우치료전적(128.3 ±72.5) ml、(5.2±1.3)ml/s、(8.4±1.2) ml/s、(18.1±1.2)cm H2O(t =4.01、4.21、3.45、3.52、3.68、3.47、3.33、3.24,균P＜0.01).결론 α-류신산연합막사필리치료당뇨병신경원성방광유교호적림상료효.
Objective To observe the efficacy of lipoic acid combined with mosapride in the treatment of diabetic neurogenic bladder.Methods 30 patients with type 2 diabetes complicated with diabatic neurogenic bladder were treated with lipoic acid and mosapride for three weeks,on the base of good controlling of blood glucose,blood lipids,and other metabolic indicators.The residual urine volume of bladder and urodynamic indicators were compared before and after treatment.Results The residual urine volume of bladder and urodynamic indicators after treatment for three weeks and withdrawal for four weeks were (62.5 ± 27.8) ml and (61.3 ± 21.6) ml,(8.3 ± 1.9) ml/s and (7.9 ±2.1)ml/s,(10.7 ± 1.8)ml/s and (10.3 ± 1.6) ml/s,(25.6 ±2.7)cm H2O and (24.5 ±2.3)cm H2O,which were significiantly better than those before treatment [(128.3 ± 72.5) ml,(5.2 ± 1.3) ml/s,(8.4 ± 1.2) ml/s,(18.1 ±1.2)cm H2O](t=4.01,4.21,3.45,3.52,3.68,3.47,3.33,3.24,all P ＜0.01).Conclusion Lipoic acid combined with mosapride has good effect in the treatment of diabetic neurogenic bladder.
