中国保健营养（中旬刊）
中國保健營養（中旬刊）
중국보건영양（중순간）
China Hwalth Care & nutrition
2013年
9期
45-45,46
,共2页
右美托咪定%氯胺酮%小儿麻醉%躁动%谵妄
右美託咪定%氯胺酮%小兒痳醉%躁動%譫妄
우미탁미정%록알동%소인마취%조동%섬망
Dexmedetomidine%Ketamine%Pediatric anesthesia%Agitation%Delirium
目的：观察右美托咪定复合氯胺酮小儿麻醉患者的术后躁动、谵妄状况。方法：选择80例小儿腹股沟斜疝患者，随机分为D组（右美托咪定组）和M组（咪达唑仑组），每组40例。D组术前泵入右美托咪定1mg/kg(15分钟），M组术前缓慢静注咪达唑仑0.05mg/kg。两组皮肤消毒前缓慢静注氯胺酮2mg/kg后，以4mg/(kg·h)输液泵维持。钳夹皮肤反应消失后手术，术毕停药。记录手术时间、苏醒时间及术后躁动、谵妄状况。结果：两组手术时间、苏醒时间差异无显著性意义（P＞0.05）；D组苏醒期躁动、谵妄发生率明显少于M组（P＜0.01），术后6h谵妄发生率少于M组（P＜0.05）。结论：右美托咪定复合氯胺酮小儿麻醉，术后躁动、谵妄发生率降低，效果优于咪达唑仑。
目的：觀察右美託咪定複閤氯胺酮小兒痳醉患者的術後躁動、譫妄狀況。方法：選擇80例小兒腹股溝斜疝患者，隨機分為D組（右美託咪定組）和M組（咪達唑崙組），每組40例。D組術前泵入右美託咪定1mg/kg(15分鐘），M組術前緩慢靜註咪達唑崙0.05mg/kg。兩組皮膚消毒前緩慢靜註氯胺酮2mg/kg後，以4mg/(kg·h)輸液泵維持。鉗夾皮膚反應消失後手術，術畢停藥。記錄手術時間、囌醒時間及術後躁動、譫妄狀況。結果：兩組手術時間、囌醒時間差異無顯著性意義（P＞0.05）；D組囌醒期躁動、譫妄髮生率明顯少于M組（P＜0.01），術後6h譫妄髮生率少于M組（P＜0.05）。結論：右美託咪定複閤氯胺酮小兒痳醉，術後躁動、譫妄髮生率降低，效果優于咪達唑崙。
목적：관찰우미탁미정복합록알동소인마취환자적술후조동、섬망상황。방법：선택80례소인복고구사산환자，수궤분위D조（우미탁미정조）화M조（미체서륜조），매조40례。D조술전빙입우미탁미정1mg/kg(15분종），M조술전완만정주미체서륜0.05mg/kg。량조피부소독전완만정주록알동2mg/kg후，이4mg/(kg·h)수액빙유지。겸협피부반응소실후수술，술필정약。기록수술시간、소성시간급술후조동、섬망상황。결과：량조수술시간、소성시간차이무현저성의의（P＞0.05）；D조소성기조동、섬망발생솔명현소우M조（P＜0.01），술후6h섬망발생솔소우M조（P＜0.05）。결론：우미탁미정복합록알동소인마취，술후조동、섬망발생솔강저，효과우우미체서륜。
Objective:To observe the condition of dexmedetomidine combined with ketamine on post-surgical agitation and delirium in pediatric anesthesia. Methods:Eighty infantile inguinal hernia patients were randomly divided into group D (dexmedetomidine group) and group M (midazolam group), 40 cases in each group. Before surgical, 1mg/kg of dexmedetomidine were pumped into children of group D (15 minutes), 0.05mg/kg of midazolam were intravenous injection into children of group M. Before the skin disinfection ,two groups were administrated intravenously ketamine 2mg/kg, then 4 mg/(kg·h) of ketamine were pumped to maintain. Beginning surgery after clamps skin reaction disappeared, at the end of the surgery to stop ketamine pumping. The operation time, awakening time, agitation and delirium of postoperative were recorded. Results:The two groups of operation time, awakening time had no significantly difference (P>0.05);Compared with group M, the incidences of agitation and delirium during emergence from anesthesia were significantly decreased in group D(P < 0.01), the incidences of postoperative delirium with in 6 h after operation were significantly decreased in group D(P<0.05). Conclusion:Dexmedetomidine combined with ketamine can reduce the occurrence of postoperative agitation and delirium in pediatric anesthesia, the effect is bet er than that of midazolam.
