当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
5期
41-42
,共2页
急性胰腺炎%参麦注射液%生长抑素
急性胰腺炎%參麥註射液%生長抑素
급성이선염%삼맥주사액%생장억소
Acute pancreatitis%Shenmai injection%Somatostatin
目的：观察参麦注射液辅助治疗急性胰腺炎的效果。方法选择2011年1月-2013年1月治疗的急性胰腺炎患者52例，将其随机分为观察组与对照组，各26例。对照组患者接受生长抑素治疗，观察组患者在生长抑素治疗的基础上加用参麦注射液进行辅助治疗，行静脉滴注40 ml，1个疗程2周。观察两组患者的血淀粉酶、胰腺影像学的变化、肿瘤坏死因子α以及C反应蛋白的变化。结果两组患者在治疗后的血淀粉酶及炎症指标均有明显改善，观察组的血清AMY、CRP及TNF-α的水平分别为（32.6±4.9）U/L、（25.4±1.2）mg/L、（27.3±0.9）ng/L明显优于对照组的(36.8±6.1) U/L,(27.2±1.3) mg/L和(40.4±1.8) ng/L（P＜0.05）；此外，观察组患者治疗总有效率为96.15%，明显高于对照组的69.23%（P＜0.05）。结论参麦注射液辅助治疗急性胰腺炎效果佳，能够使患者病情得到明显改善。
目的：觀察參麥註射液輔助治療急性胰腺炎的效果。方法選擇2011年1月-2013年1月治療的急性胰腺炎患者52例，將其隨機分為觀察組與對照組，各26例。對照組患者接受生長抑素治療，觀察組患者在生長抑素治療的基礎上加用參麥註射液進行輔助治療，行靜脈滴註40 ml，1箇療程2週。觀察兩組患者的血澱粉酶、胰腺影像學的變化、腫瘤壞死因子α以及C反應蛋白的變化。結果兩組患者在治療後的血澱粉酶及炎癥指標均有明顯改善，觀察組的血清AMY、CRP及TNF-α的水平分彆為（32.6±4.9）U/L、（25.4±1.2）mg/L、（27.3±0.9）ng/L明顯優于對照組的(36.8±6.1) U/L,(27.2±1.3) mg/L和(40.4±1.8) ng/L（P＜0.05）；此外，觀察組患者治療總有效率為96.15%，明顯高于對照組的69.23%（P＜0.05）。結論參麥註射液輔助治療急性胰腺炎效果佳，能夠使患者病情得到明顯改善。
목적：관찰삼맥주사액보조치료급성이선염적효과。방법선택2011년1월-2013년1월치료적급성이선염환자52례，장기수궤분위관찰조여대조조，각26례。대조조환자접수생장억소치료，관찰조환자재생장억소치료적기출상가용삼맥주사액진행보조치료，행정맥적주40 ml，1개료정2주。관찰량조환자적혈정분매、이선영상학적변화、종류배사인자α이급C반응단백적변화。결과량조환자재치료후적혈정분매급염증지표균유명현개선，관찰조적혈청AMY、CRP급TNF-α적수평분별위（32.6±4.9）U/L、（25.4±1.2）mg/L、（27.3±0.9）ng/L명현우우대조조적(36.8±6.1) U/L,(27.2±1.3) mg/L화(40.4±1.8) ng/L（P＜0.05）；차외，관찰조환자치료총유효솔위96.15%，명현고우대조조적69.23%（P＜0.05）。결론삼맥주사액보조치료급성이선염효과가，능구사환자병정득도명현개선。
Objective To explore the clinical effect of Shenmai injection used in patients with acute pancreatitis. Methods 52 cases with serious acute pancreatitis from January 2011 to January 2013 were randomly divided into two groups, observation group and control group, and 26 cases in each. All patients were treated by somatostatintherapy, patients in the observation group given Shenmai injection treatment,to intravenous infusion of 40 ml,1 course of treatment for 2 weeks. The pancreatic imaging changes were observed and the serum levels of amylase (AMY), C reactive protein (CRP) and tumor necrosis factor-α(TNF-α) were tested. Results Two groups of patients after treatment of blood amylase and inlfammation index were improved signiifcantly,the observation group serum AMY, CRP and TNF-αthe level of respectively were (32.6±4.9) U/L, (25.4±1.2) mg/L and (27.3±0.9) ng/L, signiifcantly better than the control group(36.8±6.1) U/L, (27.2±1.3) mg/L and (40.4±1.8) ng/L (P<0.05);In addition, the observation group of patients treatment the total effective rate was 96.15%, signiifcantly higher than the control group 69.23%(P<0.05). Conclusion The therapy of shenmai injection is effective and safe,and can signiifcantly improve the states of patients with acute pancreatitis.
