CAJ | 학술논문

目的：探讨分析磁共振弥散张量白质纤维束示踪成像对急性脑梗死患者康复的评估价值。方法：回顾性分析2010年10月-2012年12月郑州市第二人民医院神经内科明确诊断为脑梗死的75例患者的临床资料，利用磁共振扫描仪，对脑梗死患者进行常规磁共振（magnetic resonance imaging, MRI），依照皮质脊髓束受累情况将患者分成三组，在患者起病后的不同时期，发病后3 d内（急性期）、发病后8~14 d（慢性早期）、发病后30~60 d（慢性期）依照美国国立卫生院卒中量表（Nation Institutes of Health Stroke Scale, NIHSS）对患者进行神经功能评分，利用统计学方法对不同级别皮质脊髓束损伤组患者不同时期的神经功能评分分别进行比较，评价该神经束的受累情况与脑梗死患者预后变化的关系。结果：随着发病时间的不断延长，三组患者的NIHSS评分均呈现明显降低的趋势，差异有统计学意义（P<0.05）。组间比较发现，在不同时期，B、C组患者的NIHSS评分均显著高于A组，组间比较差异均有统计学意义（P<0.05）；C患者的NIHSS评分均显著高于B组，两组比较差异均有统计学意义（P<0.05）。结论：磁共振弥散张量白质纤维束示踪成像可准确定位梗死灶，有助于预测急性脑梗死患者运动功能的恢复，值得在临床上推广应用。
목적：탐토분석자공진미산장량백질섬유속시종성상대급성뇌경사환자강복적평고개치。방법：회고성분석2010년10월-2012년12월정주시제이인민의원신경내과명학진단위뇌경사적75례환자적림상자료，이용자공진소묘의，대뇌경사환자진행상규자공진（magnetic resonance imaging, MRI），의조피질척수속수루정황장환자분성삼조，재환자기병후적불동시기，발병후3 d내（급성기）、발병후8~14 d（만성조기）、발병후30~60 d（만성기）의조미국국립위생원졸중량표（Nation Institutes of Health Stroke Scale, NIHSS）대환자진행신경공능평분，이용통계학방법대불동급별피질척수속손상조환자불동시기적신경공능평분분별진행비교，평개해신경속적수루정황여뇌경사환자예후변화적관계。결과：수착발병시간적불단연장，삼조환자적NIHSS평분균정현명현강저적추세，차이유통계학의의（P<0.05）。조간비교발현，재불동시기，B、C조환자적NIHSS평분균현저고우A조，조간비교차이균유통계학의의（P<0.05）；C환자적NIHSS평분균현저고우B조，량조비교차이균유통계학의의（P<0.05）。결론：자공진미산장량백질섬유속시종성상가준학정위경사조，유조우예측급성뇌경사환자운동공능적회복，치득재림상상추엄응용。
evaluated according to nation institutes of health stroke scale(NIHSS), which were contrastively analyzed between different time points and groups using statistical methods. Result:NIHSS scores of patients in all groups showed rising trend following time, and the difference between time points had statistically significant(P<0.05). Compared among groups, the NIHSS score of the second group was significantly higher than that of the first group(P<0.05), and that of the third group were significantly higher than that of the second group too(P<0.05). Conclusion:White matter tractography by diffusion tensor imaging can accurately position infarction lesions and help to predict the recovery of motor function of patients with acute cerebral infarction, which was worthy of clinical popularization and application.