中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
7期
71-73
,共3页
精神分裂症%低频重复经颅磁刺激%顽固性幻听
精神分裂癥%低頻重複經顱磁刺激%頑固性幻聽
정신분렬증%저빈중복경로자자격%완고성환은
Schizophrenia%Low-frequency repetitive transcranial magnetic stimulation%Refractory auditory hallucination
目的：分析双背侧前额叶低频重复经颅磁刺激治疗精神分裂症顽固性幻听的临床效果。方法：选取本院2012年3月-2013年3月收治的28例精神分裂症顽固性幻听患者，按照随机数字表法将其分成对照组和观察组各14例，对照组采用1 Hz伪刺激治疗，观察组采用1 Hz真刺激治疗，分析比较两组患者的治疗效果。结果：观察组的幻听症状、精神病理症状以及总评分改善情况均明显优于对照组，差异均有统计学意义（P<0.05）。幻听症状改善主要表现在：观察组患者的幻听声音大小以及频率改善情况明显优于对照组，且患者的抑郁、焦虑等精神病理症状和意志活动方面的阴性症状均较对照组有所改善，比较差异均有统计学意义（P<0.05）。结论：1 Hz的双背侧前额叶低频重复经颅磁刺激（rTMS）治疗精神分裂症顽固性幻听效果显著，且安全系数高，值得深入研究。
目的：分析雙揹側前額葉低頻重複經顱磁刺激治療精神分裂癥頑固性幻聽的臨床效果。方法：選取本院2012年3月-2013年3月收治的28例精神分裂癥頑固性幻聽患者，按照隨機數字錶法將其分成對照組和觀察組各14例，對照組採用1 Hz偽刺激治療，觀察組採用1 Hz真刺激治療，分析比較兩組患者的治療效果。結果：觀察組的幻聽癥狀、精神病理癥狀以及總評分改善情況均明顯優于對照組，差異均有統計學意義（P<0.05）。幻聽癥狀改善主要錶現在：觀察組患者的幻聽聲音大小以及頻率改善情況明顯優于對照組，且患者的抑鬱、焦慮等精神病理癥狀和意誌活動方麵的陰性癥狀均較對照組有所改善，比較差異均有統計學意義（P<0.05）。結論：1 Hz的雙揹側前額葉低頻重複經顱磁刺激（rTMS）治療精神分裂癥頑固性幻聽效果顯著，且安全繫數高，值得深入研究。
목적：분석쌍배측전액협저빈중복경로자자격치료정신분렬증완고성환은적림상효과。방법：선취본원2012년3월-2013년3월수치적28례정신분렬증완고성환은환자，안조수궤수자표법장기분성대조조화관찰조각14례，대조조채용1 Hz위자격치료，관찰조채용1 Hz진자격치료，분석비교량조환자적치료효과。결과：관찰조적환은증상、정신병리증상이급총평분개선정황균명현우우대조조，차이균유통계학의의（P<0.05）。환은증상개선주요표현재：관찰조환자적환은성음대소이급빈솔개선정황명현우우대조조，차환자적억욱、초필등정신병리증상화의지활동방면적음성증상균교대조조유소개선，비교차이균유통계학의의（P<0.05）。결론：1 Hz적쌍배측전액협저빈중복경로자자격（rTMS）치료정신분렬증완고성환은효과현저，차안전계수고，치득심입연구。
Objective:To analyze clinical effect on the double dorsal prefrontal low-frequency repetitive transcranial magnetic stimulation in the treatment of refractory auditory hallucination in patients with schizophrenia.Method:A total of 28 schizophrenia patients with refractory auditory hallucination in our hospital from March 2012 to March 2013 were selected, and they were divided into the control group and the observation group randomly,and the control group was given pseudo stimulation with 1 Hz,and the observation group was given real stimulation with 1 Hz,and then the therapeutic effects of the two groups were analyzed and compared.Result:The auditory hallucination symptoms,mental pathological symptoms and the total scores in the observation group after the treatment improvement were significantly better than those in the control group, the differences were statistically significant(P<0.05).The main improvements of auditory hallucination symptoms:the auditory hallucinations sound size and frequency significantly in the observation group were higher than those in control group, and patients with depression,anxiety and other psychiatric symptoms and negative symptoms of bulesis activities were improved,the differences were statistically significant(P<0.05).Conclusion:The double dorsal prefrontal low frequency repetitive transcranial magnetic stimulation(rTMS)with 1 Hz has a remarkable treatment effect in refractory schizophrenia auditory hallucination,and it has a high safety coefficient,is worthy of further studying.
