中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
7期
25-26
,共2页
黄斌%王朋朋%吴淑庄%李贵才%谢鹤
黃斌%王朋朋%吳淑莊%李貴纔%謝鶴
황빈%왕붕붕%오숙장%리귀재%사학
血清尘螨特异性IgE%小儿哮喘%检查%诊断%防治
血清塵螨特異性IgE%小兒哮喘%檢查%診斷%防治
혈청진만특이성IgE%소인효천%검사%진단%방치
Allergen specific IgE in serum%Asthma%Examination%Diagnosis%Prevention and cure
目的：探讨血清尘螨特异性IgE检测在小儿哮喘诊断与防治中的应用。方法：选取本院在2009年3月-2012年10月收治的52例小儿哮喘患儿为观察组，其中<3岁者11例，4~6岁者18例，7~12岁者23例；选取正常儿童44例作为对照组，其中<3岁者8例，4~6岁者16例，7~12岁者20例。两组儿童均进行血清尘螨特异性IgE检测，比较其结果。结果：观察组患儿的血清尘螨特异性IgE浓度为（152.78±48.95）U/mL；对照组儿童的血清尘螨特异性IgE浓度为（25.62±6.49）U/mL，观察组患儿的血清尘螨特异性IgE浓度明显高于对照组，差异有统计学意义（P<0.01）。结论：小儿哮喘患儿的血清尘螨特异性IgE阳性率很高，尤其7~12岁患儿阳性率最高，所以尘螨过敏原是诱发小儿哮喘的重要因素，通过血清尘螨特异性IgE检查有助于发现尘螨过敏原，对防治由尘螨过敏原诱发小儿哮喘的重要手段，值得临床推广应用。
目的：探討血清塵螨特異性IgE檢測在小兒哮喘診斷與防治中的應用。方法：選取本院在2009年3月-2012年10月收治的52例小兒哮喘患兒為觀察組，其中<3歲者11例，4~6歲者18例，7~12歲者23例；選取正常兒童44例作為對照組，其中<3歲者8例，4~6歲者16例，7~12歲者20例。兩組兒童均進行血清塵螨特異性IgE檢測，比較其結果。結果：觀察組患兒的血清塵螨特異性IgE濃度為（152.78±48.95）U/mL；對照組兒童的血清塵螨特異性IgE濃度為（25.62±6.49）U/mL，觀察組患兒的血清塵螨特異性IgE濃度明顯高于對照組，差異有統計學意義（P<0.01）。結論：小兒哮喘患兒的血清塵螨特異性IgE暘性率很高，尤其7~12歲患兒暘性率最高，所以塵螨過敏原是誘髮小兒哮喘的重要因素，通過血清塵螨特異性IgE檢查有助于髮現塵螨過敏原，對防治由塵螨過敏原誘髮小兒哮喘的重要手段，值得臨床推廣應用。
목적：탐토혈청진만특이성IgE검측재소인효천진단여방치중적응용。방법：선취본원재2009년3월-2012년10월수치적52례소인효천환인위관찰조，기중<3세자11례，4~6세자18례，7~12세자23례；선취정상인동44례작위대조조，기중<3세자8례，4~6세자16례，7~12세자20례。량조인동균진행혈청진만특이성IgE검측，비교기결과。결과：관찰조환인적혈청진만특이성IgE농도위（152.78±48.95）U/mL；대조조인동적혈청진만특이성IgE농도위（25.62±6.49）U/mL，관찰조환인적혈청진만특이성IgE농도명현고우대조조，차이유통계학의의（P<0.01）。결론：소인효천환인적혈청진만특이성IgE양성솔흔고，우기7~12세환인양성솔최고，소이진만과민원시유발소인효천적중요인소，통과혈청진만특이성IgE검사유조우발현진만과민원，대방치유진만과민원유발소인효천적중요수단，치득림상추엄응용。
Obiective:To explore the application of blood dust mite specific IgE detection in the diagnosis and treatment of children asthma.Method:52 children with asthma from March 2009 to October 2012 were selected in our hospital as the observation group,there were 11 cases<3 years old,18 cases in 4-6 years old,and 23 cases in 7-12 years old;And 44 normal children were selected as the control group,there were 8 cases<3 years old,16 cases in 4-6 years old, and 20 cases in 7-12 years old.Two groups were tested serum dust mite specific IgE and the results were compared.Result:The serum concentration of mite specific IgE in the observation group was(152.78±48.95)U/mL;serum concentration of mite specific IgE in the control group was(25.62±6.49)U/mL,the serum concentration of mite specific IgE in observation group was significantly higher than that in control group,the difference was statistically significant(P<0.01).Conclusion:There is a high positive rate of serum dust mite specific IgE in children with asthma,especially in children of 7-12 years old, so that the dust mite allergen is an important factor that induced asthma in children,serum dust mite specific IgE examination is helpful to the discovery of dust mite allergen,it is an important way to prevent from dust mite allergen induced asthma in children,it is worthy of clinical application.
