世界最新医学信息文摘（电子版）
世界最新醫學信息文摘（電子版）
세계최신의학신식문적（전자판）
World Latest Medicine Information
2013年
24期
16-18
,共3页
药物性肝损伤%超声检查%临床应用
藥物性肝損傷%超聲檢查%臨床應用
약물성간손상%초성검사%림상응용
drug-indueed liver injury%Ultrasonography%clinical application
目的：探讨超声影像学检查在药物性肝损伤诊断、损伤程度及治疗效果评估中的应用价值。方法收集2009年至2013年的20例药物性肝损伤病例，对比分析病人治疗前后，生化检测指标及肝脏超声表现。结果肝脏超声表现及生化指标均提示病例为肝细胞损伤型肝损伤。依据生化指标检测结果分为，轻度肝损害5例(25.0％)，中度肝损害8例(40.0％)，重度肝损害7例(35.0％)。超声声像图显示，轻度肝损伤患者无明显改变，重度肝损伤病人均合并腹腔积液。治疗后，超声复查结果显示，部分重度肝损伤患者虽肝功能好转，但存在肝脏器质性改变。结论药物性肝损伤以肝细胞损伤型多见。对于中、重度肝损伤患者，通过肝脏超声检查可提示有无脏器器质性改变及合并症，优化治疗方案；治疗后，通过监测肝脏的影像学改变，准确评估预后。
目的：探討超聲影像學檢查在藥物性肝損傷診斷、損傷程度及治療效果評估中的應用價值。方法收集2009年至2013年的20例藥物性肝損傷病例，對比分析病人治療前後，生化檢測指標及肝髒超聲錶現。結果肝髒超聲錶現及生化指標均提示病例為肝細胞損傷型肝損傷。依據生化指標檢測結果分為，輕度肝損害5例(25.0％)，中度肝損害8例(40.0％)，重度肝損害7例(35.0％)。超聲聲像圖顯示，輕度肝損傷患者無明顯改變，重度肝損傷病人均閤併腹腔積液。治療後，超聲複查結果顯示，部分重度肝損傷患者雖肝功能好轉，但存在肝髒器質性改變。結論藥物性肝損傷以肝細胞損傷型多見。對于中、重度肝損傷患者，通過肝髒超聲檢查可提示有無髒器器質性改變及閤併癥，優化治療方案；治療後，通過鑑測肝髒的影像學改變，準確評估預後。
목적：탐토초성영상학검사재약물성간손상진단、손상정도급치료효과평고중적응용개치。방법수집2009년지2013년적20례약물성간손상병례，대비분석병인치료전후，생화검측지표급간장초성표현。결과간장초성표현급생화지표균제시병례위간세포손상형간손상。의거생화지표검측결과분위，경도간손해5례(25.0％)，중도간손해8례(40.0％)，중도간손해7례(35.0％)。초성성상도현시，경도간손상환자무명현개변，중도간손상병인균합병복강적액。치료후，초성복사결과현시，부분중도간손상환자수간공능호전，단존재간장기질성개변。결론약물성간손상이간세포손상형다견。대우중、중도간손상환자，통과간장초성검사가제시유무장기기질성개변급합병증，우화치료방안；치료후，통과감측간장적영상학개변，준학평고예후。
Objective to explore the application value of ultrasound imaging in the diagnosis of drug-induced liver injury, injury severity and evaluate the therapeutic effect. Methods from 2009 to 2014 20 cases of drug-induced liver injury cases, comparative analysis of patients before and after treatment, biochemical parameters and liver ultrasound findings. Results liver ultrasound findings and biochemical indexes showed that liver injury to liver cell damage type. According to the test results of biochemical indicators divided into,mild liver damage in 5 cases (25%), 8 patients with moderate to liver damage (40%), 7 cases of severe liver damage (35%). Ultrasonographic display, no significant changes in patients with mild liver injury, severe liver injury complicated with ascites. after treatment, repeated ultrasound examination, results show, some patients with severe liver injury is the improvement of liver function, but the presence of liver organic changes.Conclusion drug induced liver injury is the main type in hepatocellular damage type. for moderate to severe liver injury patients, through the liver ultrasonography may suggest no organ for change and the merge of matter, optimization of treatment;after treatment, changes of liver image by monitoring, accurate assessment of prognosis.
