中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
14期
1-3,4
,共4页
胶质瘤%弥散张量成像%风险%评估
膠質瘤%瀰散張量成像%風險%評估
효질류%미산장량성상%풍험%평고
Gliomas%Diffusion tensor imaging%Risk%Assess
目的：研究弥散张量成像对胶质瘤手术切除程度及预后的早期评估。方法：选取在山西医科大学第一临床医学院神经外科住院手术治疗，且在术中影像学基础上达到尽全切，剔除术后3个月肿瘤进展病例后符合标准的20例患者，年龄42~79岁，平均（57.95±10.82）岁，其中男11例，女9例。采用直接测量法及弥散张量成像（DTI）辅助测量法对20例胶质瘤患者行术前、术后72 h及术后3个月的扫描，在术后MRT1加权像上不同层面分别手工描记残余肿瘤边界，获取术后72 h及术后3个月残余肿瘤体积进行比较分析。结果：经直接测量法获取术后72 h残余肿瘤体积明显大于DTI辅助测量法获取的术后72 h残余肿瘤，差异有统计学意义（t=4.924，P<0.001），直接测量法获取术后3个月残余肿瘤体积明显大于DTI辅助测量法获取的术后3个月的残余肿瘤，差异有统计学意义（t=2.311，P=0.026）。经直接测量法获取的术后72 h残余肿瘤体积明显大于术后3个月的残余肿瘤，差异有统计学意义（t=10.013，P<0.001），经DTI辅助测量法获取的术后72 h残余肿瘤体积明显大于术后3个月的残余肿瘤，差异有统计学意义（t=7.389，P<0.001）。结论：将DTI技术用于评估胶质瘤手术切除程度，能够保护患者的神经系统功能，提高手术疗效评估的准确性。
目的：研究瀰散張量成像對膠質瘤手術切除程度及預後的早期評估。方法：選取在山西醫科大學第一臨床醫學院神經外科住院手術治療，且在術中影像學基礎上達到儘全切，剔除術後3箇月腫瘤進展病例後符閤標準的20例患者，年齡42~79歲，平均（57.95±10.82）歲，其中男11例，女9例。採用直接測量法及瀰散張量成像（DTI）輔助測量法對20例膠質瘤患者行術前、術後72 h及術後3箇月的掃描，在術後MRT1加權像上不同層麵分彆手工描記殘餘腫瘤邊界，穫取術後72 h及術後3箇月殘餘腫瘤體積進行比較分析。結果：經直接測量法穫取術後72 h殘餘腫瘤體積明顯大于DTI輔助測量法穫取的術後72 h殘餘腫瘤，差異有統計學意義（t=4.924，P<0.001），直接測量法穫取術後3箇月殘餘腫瘤體積明顯大于DTI輔助測量法穫取的術後3箇月的殘餘腫瘤，差異有統計學意義（t=2.311，P=0.026）。經直接測量法穫取的術後72 h殘餘腫瘤體積明顯大于術後3箇月的殘餘腫瘤，差異有統計學意義（t=10.013，P<0.001），經DTI輔助測量法穫取的術後72 h殘餘腫瘤體積明顯大于術後3箇月的殘餘腫瘤，差異有統計學意義（t=7.389，P<0.001）。結論：將DTI技術用于評估膠質瘤手術切除程度，能夠保護患者的神經繫統功能，提高手術療效評估的準確性。
목적：연구미산장량성상대효질류수술절제정도급예후적조기평고。방법：선취재산서의과대학제일림상의학원신경외과주원수술치료，차재술중영상학기출상체도진전절，척제술후3개월종류진전병례후부합표준적20례환자，년령42~79세，평균（57.95±10.82）세，기중남11례，녀9례。채용직접측량법급미산장량성상（DTI）보조측량법대20례효질류환자행술전、술후72 h급술후3개월적소묘，재술후MRT1가권상상불동층면분별수공묘기잔여종류변계，획취술후72 h급술후3개월잔여종류체적진행비교분석。결과：경직접측량법획취술후72 h잔여종류체적명현대우DTI보조측량법획취적술후72 h잔여종류，차이유통계학의의（t=4.924，P<0.001），직접측량법획취술후3개월잔여종류체적명현대우DTI보조측량법획취적술후3개월적잔여종류，차이유통계학의의（t=2.311，P=0.026）。경직접측량법획취적술후72 h잔여종류체적명현대우술후3개월적잔여종류，차이유통계학의의（t=10.013，P<0.001），경DTI보조측량법획취적술후72 h잔여종류체적명현대우술후3개월적잔여종류，차이유통계학의의（t=7.389，P<0.001）。결론：장DTI기술용우평고효질류수술절제정도，능구보호환자적신경계통공능，제고수술료효평고적준학성。
Objective:To evaluate the utility of diffusion tensor imaging(DTI)in early assessment of extent of surgical resection and prognosis of gliomas surgical.Method:Selected the patients who were given operation treatment in neurosurgical department in first Clinical College of Shanxi Medical University,achieved the full cut based on the best imaging technique in operation and excluded tumor progression cases after 3 months,a total of 20 patients up to the standard.Patients were 42 to 79 years old,the average age was(57.95±10.82)years old,including 11 males and 9 females.The scanning of 20 glioma patients with preoperative and postoperative 72 hours and 3 months were performed by direct measurement and diffusion tensor imaging(DTI)auxiliary measurements.Tracings tumor boundaries with hand on different levels of postoperative MRT1 weighted images.Residual tumor volume after 72 hours and 3 months were analyzed and compared.Result:The volume of residual tumor after 72 hours by direct measurement was significantly larger than that by DTI acquiring auxiliary measurement,the difference was statistically significant(t=4.924,P<0.001). The volume of residual tumor after 3 months by direct measurement was significantly larger than that by DTI acquiring auxiliary measurement,the difference was statistically significant(t=2.311,P=0.026).The volume of residual tumor after 72 hours by direct measurement was significantly larger than that after 3 months,the difference was statistically significant(t=10.013,P<0.001).The volume of residual tumor after 72 hours by DTI acquiring auxiliary measurement was significantly larger than that after 3 months,the difference was statistically significant(t=7.389,P<0.001). Conclusion:DTI can be used in assessing the extent of surgical resection of gliomas to protect the nervous system function and improve the accuracy of surgery assessment.
