CAJ | 학술논문

目的：评价米力农治疗肺心病急性加重期疗效。方法83例随机分为两组，均在相同常规治疗基础上，治疗组加用米力农10mg溶入5％葡萄糖250ml中静脉滴注，1次/d，10d为一疗程。观察组加用5％葡萄糖250 ml静脉滴注，1次/d。10 d后观察比较两组间的治疗前后动脉血气分析，并用心脏彩超测量肺动脉平均压力及左心室射血分数变化及临床综合评价心肺功能改善有效率。结果治疗组的动脉血气分析指标改善，肺动脉压力及左心功能指标的改善及综合评价心肺功能好转的有效率显著优于对照组（ P均＜0.05），其中PaO2、临床心功改善比较差异均有统计学意义（ P ＜0.01）。结论米力农治疗肺心病急性加重期效果满意。
목적：평개미력농치료폐심병급성가중기료효。방법83례수궤분위량조，균재상동상규치료기출상，치료조가용미력농10mg용입5％포도당250ml중정맥적주，1차/d，10d위일료정。관찰조가용5％포도당250 ml정맥적주，1차/d。10 d후관찰비교량조간적치료전후동맥혈기분석，병용심장채초측량폐동맥평균압력급좌심실사혈분수변화급림상종합평개심폐공능개선유효솔。결과치료조적동맥혈기분석지표개선，폐동맥압력급좌심공능지표적개선급종합평개심폐공능호전적유효솔현저우우대조조（ P균＜0.05），기중PaO2、림상심공개선비교차이균유통계학의의（ P ＜0.01）。결론미력농치료폐심병급성가중기효과만의。
Objective To evaluate effection of Milrinone in patients with pneumocardial disease at acute exacerbation stage .Methods Eighty-three patients were randomly divided into two groups , both in the same conventional therapy , the treatment group received 10mg of Milrinone dissolve in 250ml 5% glu-cose intravenous infusion , 1 second /day, 10 days for a course of treatment .Observation group were treated with 5%glucose infusion 250ml, 1 time /day.The arterial blood gas, echocardiography measurements with mean pulmonary artery pressure , left ventricular ejection fraction and clinical evaluation to improve cardiop-ulmonary function efficiently were compared before and after treatment .Results Arterial blood gas analy-sis, pulmonary artery pressure and left ventricular function were improved and comprehensive evaluation of the efficiency of cardiopulmonary function in treatment group were significantly better than the control group ( Pall<0.05).Conclusion There is satisfactory of Milrinone in acute exacerbation of chronic pulmonary heart disease .