CAJ | 학술논문

目的：评价长脉冲1064 nm Nd：YAG激光、二氧化碳激光及液氮冷冻治疗化脓性肉芽肿的疗效及安全性。方法将137例化脓性肉芽肿患者随机分为3组，分别采用长脉冲1064 nm Nd：YAG激光(A组)、二氧化碳激光(B组)及液氮冷冻(C组)治疗，评估治疗后6个月的疗效及安全性。结果长脉冲1064 nm Nd：YAG激光、二氧化碳激光及液氮冷冻治疗化脓性肉芽肿的1次治愈率分别为86.9%、78.3%和57.8%，总治愈率分别为100%、86.9%和97.7%，不良反应发生率分别为4.3%、15.2%和13.3%。3种方法治疗化脓性肉芽肿安全有效，其中1次治愈率及总治愈率以Nd：YAG激光组最好，不良反应差异无统计学意义。结论长脉冲1064 nm Nd：YAG激光治疗化脓性肉芽肿安全有效。
목적：평개장맥충1064 nm Nd：YAG격광、이양화탄격광급액담냉동치료화농성육아종적료효급안전성。방법장137례화농성육아종환자수궤분위3조，분별채용장맥충1064 nm Nd：YAG격광(A조)、이양화탄격광(B조)급액담냉동(C조)치료，평고치료후6개월적료효급안전성。결과장맥충1064 nm Nd：YAG격광、이양화탄격광급액담냉동치료화농성육아종적1차치유솔분별위86.9%、78.3%화57.8%，총치유솔분별위100%、86.9%화97.7%，불량반응발생솔분별위4.3%、15.2%화13.3%。3충방법치료화농성육아종안전유효，기중1차치유솔급총치유솔이Nd：YAG격광조최호，불량반응차이무통계학의의。결론장맥충1064 nm Nd：YAG격광치료화농성육아종안전유효。
Objective To compare the clinical efifcacy and safety of Nd:YAG laser with CO2 laser and liquid nitrogen cryosurgery in the treatment of granuloma pyogenicum. Methods One hundred and thirty-seven cases with granuloma pyogenicum were divided into three groups, and were treated with long-pulsed Nd:YAG laser (Group A, 46 cases), CO2 laser (Group B, 46 cases) and liquid nitrogen cryosurgery (Group C, 45 cases), respectively. Efifcacy and safety evaluations were carried out 6 months after treatment. Results The cure rates after one treatment session were 86.9%, 78.3%and 57.8%in group A, B and C, respectively. The total cure rates in group A, B and C were 100%, 86.9%and 97.7%, respectively. The incidence of adverse events was 4.3%, 15.2%and 13.3%in group A, B and C respectively. All the three treatments were safe and effective in the treatment of granuloma pyogenicum, however, Nd:YAG laser treatment was the best when concerning about the total cure rate the cure rates after one treatment. There was no statistically signiifcant difference adverse reactions. Conclusion Nd:YAG laser treatment was an effective and safe method for the treatment of granuloma pyogenicum, which could be use as a ifrst-line choice.