CAJ | 학술논문

目前在世界范围内花生过敏的致命发生率有所增加。花生过敏症是由免疫球蛋白E(IgE)对花生蛋白质产生的过敏性反应，过敏原主要是通过摄食，其次为通过皮肤接触和吸入进入体内。临床症状经常涉及多个系统，包括皮肤、心血管、消化和呼吸系统。诊断花生过敏的第一步是详细询问病史和体格检查，诊断试验包括皮肤点刺试验(SPT)、体外花生特异性IgE测定、直接进食花生试验。花生过敏症的预防重点是教育患者及其家属避免接触含有花生成分的产品，此外还应该了解过敏反应的早期体征，学会对过敏症状的初步治疗，以及长期随访。目前，临床医生正在研究具有良好应用前景的新的免疫治疗方案。
목전재세계범위내화생과민적치명발생솔유소증가。화생과민증시유면역구단백E(IgE)대화생단백질산생적과민성반응，과민원주요시통과섭식，기차위통과피부접촉화흡입진입체내。림상증상경상섭급다개계통，포괄피부、심혈관、소화화호흡계통。진단화생과민적제일보시상세순문병사화체격검사，진단시험포괄피부점자시험(SPT)、체외화생특이성IgE측정、직접진식화생시험。화생과민증적예방중점시교육환자급기가속피면접촉함유화생성분적산품，차외환응해료해과민반응적조기체정，학회대과민증상적초보치료，이급장기수방。목전，림상의생정재연구구유량호응용전경적신적면역치료방안。
Allergic reactions to peanuts in children have become a significant medical and legal concern worldwide, with a rising incidence of this potentially fatal condition. Peanut allergy represents an immunoglobulin E (IgE) mediated hypersensitivity reaction to peanut proteins. Exposure to the allergen was most commonly through ingestion, followed by presumed skin contact and inhalation. Clinical reactions frequently involve multiple organs including the cutaneous, cardiovascular, gastrointestinal, and respiratory systems. The ifrst step in identifying peanut as the cause of a reaction is a detailed history and physical examination. Detection of peanut-speciifc IgE by either skin prick test (SPT) or in vitro assays can help with diagnosis. Management of peanut allergy centers on educating patients and their families on complete avoidance of peanut-containing products, and have recognition of early signs of an allergic reaction, know the treatment of early stages of allergic symptoms, and follow-up long-term. New immunotherapeutic options are being investigated and appear promising.