CAJ | 학술논문

目的：分析血糖变异性与不同程度脓毒症28 d死亡率间的关系．方法2010年9月至2012年9月入住急诊ICU时诊断为脓毒症，且至少在急诊ICU住院3 d以上的成年患者均入选，剔除达到排除标准的患者后，从剩余患者病历中提取血糖值及所需临床资料．计算每例患者的最高血糖、平均血糖及血糖标准差，根据患者脓毒症严重程度分组，统计学分析这些指标与28 d死亡率的关系．结果血糖标准差与28 d死亡率间有重要关联（OR＝4.237，＝0.021），脓毒症越严重，血糖变异性越大（＝0.016）．结论血糖变异性与脓毒症患者28 d死亡率独立相关，脓毒症严重程度与血糖变异性有积极相关性．
목적：분석혈당변이성여불동정도농독증28 d사망솔간적관계．방법2010년9월지2012년9월입주급진ICU시진단위농독증，차지소재급진ICU주원3 d이상적성년환자균입선，척제체도배제표준적환자후，종잉여환자병력중제취혈당치급소수림상자료．계산매례환자적최고혈당、평균혈당급혈당표준차，근거환자농독증엄중정도분조，통계학분석저사지표여28 d사망솔적관계．결과혈당표준차여28 d사망솔간유중요관련（OR＝4.237，＝0.021），농독증월엄중，혈당변이성월대（＝0.016）．결론혈당변이성여농독증환자28 d사망솔독립상관，농독증엄중정도여혈당변이성유적겁상관성．
Objective The purpose of this study was to analyze the relation of blood glucose variability and 28-day mortality in patients with different degree sepsis. Methods From September 1, 2010 to September 30, 2012, all adult patients diagnosed with sepsis and treated at least 3 days in Emergency ICU (EICU) of the first affiliated hospital of Kunming Medical University were enrolled in the study. Then the blood glucose levels and the other requisite clinical data were obtained from historical electronic medical records of patients excluding the patients reached exclusive criteria. The maximum and mean of blood glucose, and the glucose variability (the standard deviation,SD of blood glucose) in each patient were calculated. The patients were assigned according to severity of sepsis, then the relationship between SD of blood glucose and 28-day mortality was statistically assessed. Results There was an important correlation between SD of blood glucose and 28-day mortality (OR=4.237, =0.021) . The glucose variability increased with the serious of sepsis ( = 0.016) . Conclusion Glucose variability is an independent predictor of 28-day mortality in septic patients. In addition, the severity of sepsis has a positive correlation with blood glucose variability.