CAJ | 학술논문

目的：探讨99mTc-MIBI SPECT与CT融合显像对孤立性肺结节（SPN）的鉴别诊断价值．方法对39例SPN患者行99mTc-MIBI-SPECT与定位CT融合显像，对显像结果进行定性及半定量分析，并根据最终诊断结果，判定该显像方法对 SPN的鉴别诊断价值．结果39例 SPN患者中13例为恶性SPN，26例良性 SPN．99mTc-MIBI-SPECT与定位CT融合显像定性分析对SPN良恶性鉴别诊断灵敏度92.31%（12/13），特异性88.46%（23/26），准确性89.74%（35/39），阳性预测值80%（12/15），阴性预测值95.83%（23/24）．受试者工作特征（ROC）曲线分析显示：以99mTc-MIBI早期摄取比值（EUR）≥1.474为鉴别SPN良恶性界值，灵敏度100%，特异性76.90%；以99mTc-MIBI延迟摄取比值（DUR）≥1.38为鉴别 SPN 良恶性界值，灵敏度100%，特异性76.90%．结论99mTc-MIBI-SPECT与定位CT融合显像对SPN的鉴别诊断有较高的临床价值．
목적：탐토99mTc-MIBI SPECT여CT융합현상대고립성폐결절（SPN）적감별진단개치．방법대39례SPN환자행99mTc-MIBI-SPECT여정위CT융합현상，대현상결과진행정성급반정량분석，병근거최종진단결과，판정해현상방법대 SPN적감별진단개치．결과39례 SPN환자중13례위악성SPN，26례량성 SPN．99mTc-MIBI-SPECT여정위CT융합현상정성분석대SPN량악성감별진단령민도92.31%（12/13），특이성88.46%（23/26），준학성89.74%（35/39），양성예측치80%（12/15），음성예측치95.83%（23/24）．수시자공작특정（ROC）곡선분석현시：이99mTc-MIBI조기섭취비치（EUR）≥1.474위감별SPN량악성계치，령민도100%，특이성76.90%；이99mTc-MIBI연지섭취비치（DUR）≥1.38위감별 SPN 량악성계치，령민도100%，특이성76.90%．결론99mTc-MIBI-SPECT여정위CT융합현상대SPN적감별진단유교고적림상개치．
Objective To investigate the diagnosis of value 99mTc-MIBI SPECT and CT fusion imaging in the differential solitary pulmonary nodule ( SPN). Methods Thirty-nine patients with SPN underwent 99mTc-MIBI-SPECT and positioning CT fusion imaging, and the imaging results carried on the qualitative and semi-quantitative analysis. The diagnostic value of the imaging method for SPN was judged according to the results of the final diagnosis. Results Of 39 cases with SPN, 13 cases were malignant and 26 cases were benign. The diagnostic sensitivity, specificity, accuracy, negative predictive value and positive predictive value of 99mTc-MIBI-SPECT positioning CT fusion imaging qualitative analysis in benign and malignant SPN was 92.31%(12/13),88.46%(23/26),89.74%(35/39),80% (12/15) and 95.83% (23/24),respectively. Receiver operating characteristic (ROC) curve analysis showed:using 99mTc-MIBI early uptake ratio (EUR) ≥1.474 as the critical value for identification the benign and malignant SPN, the sensitivity and specificity was 100% and 76.90%, respectively;using 99mTc-MIBI delayed uptake ratio (DUR) ≥ 1.38 as the critical value, the sensitivity and specificity was 100%and 76.90%. Conclusion The method of 99mTc-MIBI-SPECT and positioning CT fusion imaging has a high clinical value in the differential diagnosis of SPN.