昆明医科大学学报
昆明醫科大學學報
곤명의과대학학보
Journal of Kunming Medical University
2014年
1期
1-4
,共4页
王海垠%丁林芬%吴兴德%王双燕%何隽%赵勤实%宋流东
王海垠%丁林芬%吳興德%王雙燕%何雋%趙勤實%宋流東
왕해은%정림분%오흥덕%왕쌍연%하준%조근실%송류동
大黄藤%化学成分%结构鉴定
大黃籐%化學成分%結構鑒定
대황등%화학성분%결구감정
Fibraurea recisa%Chemical constituents%Structural identification
目的:研究大黄藤( Pierre)中的化学成分。方法利用正相硅胶柱色谱、半制备型高效液相色谱、葡聚糖凝胶及反相中压液相色谱等现代分离技术进行分离,根据理化性质和NMR,MS等方法鉴定其结构。结果从中分离得到8个化合物,分别是黄藤内酯(1),马克甾酮 A(2),环阿屯醇(3), feruloylphenethylamine (4),反式阿魏酰酪胺(5),β-谷甾醇(6),1-棕榈酸单甘油酯(7),1-sinapoyl-β-D-glucopyranoside (8)。结论化合物2~8为首次从该植物中分离得到。
目的:研究大黃籐( Pierre)中的化學成分。方法利用正相硅膠柱色譜、半製備型高效液相色譜、葡聚糖凝膠及反相中壓液相色譜等現代分離技術進行分離,根據理化性質和NMR,MS等方法鑒定其結構。結果從中分離得到8箇化閤物,分彆是黃籐內酯(1),馬剋甾酮 A(2),環阿屯醇(3), feruloylphenethylamine (4),反式阿魏酰酪胺(5),β-穀甾醇(6),1-棕櫚痠單甘油酯(7),1-sinapoyl-β-D-glucopyranoside (8)。結論化閤物2~8為首次從該植物中分離得到。
목적:연구대황등( Pierre)중적화학성분。방법이용정상규효주색보、반제비형고효액상색보、포취당응효급반상중압액상색보등현대분리기술진행분리,근거이화성질화NMR,MS등방법감정기결구。결과종중분리득도8개화합물,분별시황등내지(1),마극치동 A(2),배아둔순(3), feruloylphenethylamine (4),반식아위선락알(5),β-곡치순(6),1-종려산단감유지(7),1-sinapoyl-β-D-glucopyranoside (8)。결론화합물2~8위수차종해식물중분리득도。
Objective The purpose of this study was to investigate the chemical constituents of Pierre. Methods The chemical compositions were isolated by silica gel column chromatography, semi-preparative HPLC,Sephadex LH-20, and MPLC packed with MCI gel, and their structures were identified on the basis of chemical and spectroscopic evidence (NMR and MS) . Results Eight compounds were obtained and determined as fibraurin (1),makisterone A (2),cycloartenol (3),feruloylphenethylamine (4),trans- -feruloyltyramine(5),β-sitosterol(6),1-monopalmitin(7),1-sinapoyl-β-D-glucopyranoside(8). Conclusion Compounds 2-8 were isolated from this plant for the first time.