CAJ | 학술논문

[目的]研究原发性高血压病患者昼夜血压节律异常与左心室肥厚的相关性。[方法]选取本院2012年5～10月收治的100例原发性高血压病患者作为研究对象，所有患者经24 h动态血压监测分为杓型组与非杓型组，其中杓型组54例，非杓型组46例，比较两组患者的24 h动态血压监测的情况以及超声心动图的各项指标。[结果]非杓型组的24h SBP、24h DBP、昼间SBP、夜间SBP均明显高于杓型组，两组患者动态血压差异具有统计学意义（ P ＜0．05）；非杓型组的左心室后壁厚度（LVPW）、室间隔厚度（IVS）、左心室重量（LVM ）、左心室重量指数（LVMI）均较杓型组有着显著的增加，且差异具有统计学意义（ P ＜0．05）。[结论]原发性高血压病患者昼夜血压节律异常对于左心室肥厚的发生、发展有着明显的促进作用，显著影响左心室的舒张功能。
[목적]연구원발성고혈압병환자주야혈압절률이상여좌심실비후적상관성。[방법]선취본원2012년5～10월수치적100례원발성고혈압병환자작위연구대상，소유환자경24 h동태혈압감측분위표형조여비표형조，기중표형조54례，비표형조46례，비교량조환자적24 h동태혈압감측적정황이급초성심동도적각항지표。[결과]비표형조적24h SBP、24h DBP、주간SBP、야간SBP균명현고우표형조，량조환자동태혈압차이구유통계학의의（ P ＜0．05）；비표형조적좌심실후벽후도（LVPW）、실간격후도（IVS）、좌심실중량（LVM ）、좌심실중량지수（LVMI）균교표형조유착현저적증가，차차이구유통계학의의（ P ＜0．05）。[결론]원발성고혈압병환자주야혈압절률이상대우좌심실비후적발생、발전유착명현적촉진작용，현저영향좌심실적서장공능。
[Objective] To study the correlation between abnormal circadian blood pressure rhythm and left ventricular hypertrophy .[Methods] Totally 100 patients with essential hypertension in our hospital from May 2012 to Oct .2013 were selected as the study subjects .All patients were divided into dipper group ( n =54) and non-dipper group( n=46) by 24h-ambulatory blood pressure monitoring .The 24h-ambulatory blood pressure mo-nitoring situation and echocardiographic indicators were compared between two groups .[Results]The 24h SBP , 24h DBP ,day SBP and night SBP of non-dipper group were obviously higher than those of dipper group ,and there was significant difference in ambulatory blood pressure between two groups ( P < 0 .05) .Compare with dipper group ,LVPW ,IVS ,LVM and LVMI in non-dipper group increased markedly ,and there was significant differ-ence( P <0 .05) .[Conclusion] Abnormal circadian blood pressure rhythm of patients with essential hypertension play a significant role in promoting the occurrence and development of left ventricular hypertrophy .It significantly influences left ventricular diastolic function .