CAJ | 학술논문

目的：观察保肾康联合厄贝沙坦治疗2型糖尿病肾病的疗效。方法：120例2型糖尿病肾病患者随机分为治疗组和对照组，每组各60例。在常规治疗的基础上，对照组应用厄贝沙坦治疗，治疗组应用保肾康与厄贝沙坦联合治疗，疗程均为12周。分别于治疗前、治疗后检测患者的血压、血糖、血脂和肾功能。结果：治疗组治疗后控制血糖、降低血压、调节血脂、降低尿蛋白和改善肾功能的情况明显优于对照组，治疗后各指标检测结果组间比较差异具有统计学意义(P＜0.01，P＜0.05)。结论：保肾康联合厄贝沙坦治疗糖尿病肾病能较好地改善和保护肾功能，且对糖尿病肾病患者血压、血糖、血脂也有良好的改善作用。
목적：관찰보신강연합액패사탄치료2형당뇨병신병적료효。방법：120례2형당뇨병신병환자수궤분위치료조화대조조，매조각60례。재상규치료적기출상，대조조응용액패사탄치료，치료조응용보신강여액패사탄연합치료，료정균위12주。분별우치료전、치료후검측환자적혈압、혈당、혈지화신공능。결과：치료조치료후공제혈당、강저혈압、조절혈지、강저뇨단백화개선신공능적정황명현우우대조조，치료후각지표검측결과조간비교차이구유통계학의의(P＜0.01，P＜0.05)。결론：보신강연합액패사탄치료당뇨병신병능교호지개선화보호신공능，차대당뇨병신병환자혈압、혈당、혈지야유량호적개선작용。
Objective:To observe the therapeutic effects of Baoshenkang combined irbesartan for treating type 2 diabetic nephropathy. Methods:120 type 2 diabetic nephropathy patients were randomly divided into treatment group and control group with 60 patients in each group. Besides regular treatment, the patients in control group were given irbesartan, patients in treatment group were given Baoshenkang combined irbesartan, all for 12 weeks. The blood pressure, blood glucose, blood lipid and renal function of patients were respectively detected before and after treatment. Results:After treatment, glucose control, lower blood pressure, regulating blood lipid and improving renal function of treatment group were obviously better than control group (P<0.01, P<0.05).Conclusions:Treating diabetic nephropathy with Baoshenkang combined irbesartan can better improve and protect renal function;moreover, Baoshenkang combined irbesartan also has goodeffectsonimprovingbloodpressure,bloodglucose and blood lipid ofdiabetic nephropathy patients.