中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
2期
60-62
,共3页
血浆心型脂肪酸结合蛋白水平%急性冠状动脉综合征%辅助诊断
血漿心型脂肪痠結閤蛋白水平%急性冠狀動脈綜閤徵%輔助診斷
혈장심형지방산결합단백수평%급성관상동맥종합정%보조진단
Plasma levels of heart type fatty acid binding protein%Acute coronary syndrome%Auxiliary diagnosis
目的：探讨血浆心型脂肪酸结合蛋白（H-FABP）水平对急性冠状动脉综合征（ACS）辅助诊断的临床价值。方法选取2011年1月至2013年1月本院收治的ACS患者89例，设为ACS组，选取同期本院收治的稳定型心绞痛患者90例，设为稳定型心绞痛组，选取同期在本院进行健康体检的90例健康志愿者，设为健康组，比较3组研究对象的血浆H-FABP水平及不同冠状动脉狭窄程度、病变支数、ACS患者的血浆H-FABP水平。结果 ACS组患者的H-FABP水平显著高于稳定型心绞痛组和健康志愿者组，并具有显著性差异（P＜0.05）；冠状动脉狭窄重度ACS患者的H-FABP水平显著高于中度、轻度ACS患者，并具有显著性差异（P＜0.05）；多支病变ACS患者的H-FABP水平显著高于2支、1支ACS患者，并具有显著性差异（P＜0.05）。结论通过对血浆H-FABP水平的检测可以很好地判断ACS患者预后水平，对于该病的辅助诊断具有积极意义，值得临床推广。
目的：探討血漿心型脂肪痠結閤蛋白（H-FABP）水平對急性冠狀動脈綜閤徵（ACS）輔助診斷的臨床價值。方法選取2011年1月至2013年1月本院收治的ACS患者89例，設為ACS組，選取同期本院收治的穩定型心絞痛患者90例，設為穩定型心絞痛組，選取同期在本院進行健康體檢的90例健康誌願者，設為健康組，比較3組研究對象的血漿H-FABP水平及不同冠狀動脈狹窄程度、病變支數、ACS患者的血漿H-FABP水平。結果 ACS組患者的H-FABP水平顯著高于穩定型心絞痛組和健康誌願者組，併具有顯著性差異（P＜0.05）；冠狀動脈狹窄重度ACS患者的H-FABP水平顯著高于中度、輕度ACS患者，併具有顯著性差異（P＜0.05）；多支病變ACS患者的H-FABP水平顯著高于2支、1支ACS患者，併具有顯著性差異（P＜0.05）。結論通過對血漿H-FABP水平的檢測可以很好地判斷ACS患者預後水平，對于該病的輔助診斷具有積極意義，值得臨床推廣。
목적：탐토혈장심형지방산결합단백（H-FABP）수평대급성관상동맥종합정（ACS）보조진단적림상개치。방법선취2011년1월지2013년1월본원수치적ACS환자89례，설위ACS조，선취동기본원수치적은정형심교통환자90례，설위은정형심교통조，선취동기재본원진행건강체검적90례건강지원자，설위건강조，비교3조연구대상적혈장H-FABP수평급불동관상동맥협착정도、병변지수、ACS환자적혈장H-FABP수평。결과 ACS조환자적H-FABP수평현저고우은정형심교통조화건강지원자조，병구유현저성차이（P＜0.05）；관상동맥협착중도ACS환자적H-FABP수평현저고우중도、경도ACS환자，병구유현저성차이（P＜0.05）；다지병변ACS환자적H-FABP수평현저고우2지、1지ACS환자，병구유현저성차이（P＜0.05）。결론통과대혈장H-FABP수평적검측가이흔호지판단ACS환자예후수평，대우해병적보조진단구유적겁의의，치득림상추엄。
Objective To investigate the changes of serum heart type fatty acid binding protein (H-FABP) levels in patients with acute coronary syndrome (ACS) in clinical diagnosis. Methods 89 ACS patients from 2011 January to 2013 January in our hospital were cases, group ACS, 90 patients were admitted to our hospital in stable angina pectoris, with stable angina group, select the same period 90 cases of healthy health volunteers in the hospital, as healthy group, plasma than H-FABP the level of plasma H-FABP level was 3 groups of subjects and different degree of coronary artery stenosis, number of diseased patients, ACS. Results ACS group of patients with H-FABP was signiifcantly higher than that in stable angina group and healthy volunteers, the result had signiifcant difference (P<0.05);coronary artery stenosis in patients with severe ACS H-FABP level was signiifcantly higher than that in moderate, mild ACS patients, with signiifcant difference (P<0.05);multi-vessel lesions in patients with ACS H-FABP level is signiifcantly higher than that of 2, 1 ACS patients, and has signiifcant difference (P<0.05). Conclusion Through the detection of plasma H-FABP levels can be a very good prognosis in patients with ACS, which has a positive signiifcance for the diagnosis of the disease, is worth the clinical promotion.
