CAJ | 학술논문

目的：探讨过敏性紫癜（HSP）患儿食物不耐受情况。方法采用ELISA，检测比较该地区58例HSP患儿以及23名正常儿童血清中14种食物特异性IgG （sIgG）水平，并分析不同性别、年龄患儿的不耐受阳性率及不耐受食物的分布差异。结果58例患儿食物 sIgG 阳性率为84．5％，高于对照组的13．0％，比较差异有统计学意义（P＜0．01）。HSP患儿不耐受的食物前4位依次为：鸡蛋/蛋白蛋黄（70．7％）、牛奶（53．4％）、鳕鱼（19．0％）、螃蟹（10．3％）；其中1种食物sIgG阳性18例（31．0％），2种或2种以上食物sIgG阳性31例（53．4％）。不同性别、不同年龄[低龄儿童（＜7岁）及高龄儿童（≥7岁）]食物sIgG总阳性率比较差异无统计学意义（P＞0．05），高龄儿童的螃蟹IgG阳性率较低龄儿童高（P＜0．01）。结论HSP患儿食物不耐受情况较正常儿童明显。该组HSP患儿对鸡蛋/蛋白蛋黄、牛奶、鳕鱼、螃蟹不耐受情况较为明显，可作为地区参考，高龄儿童对螃蟹的不耐受情况较低龄儿童明显。
목적：탐토과민성자전（HSP）환인식물불내수정황。방법채용ELISA，검측비교해지구58례HSP환인이급23명정상인동혈청중14충식물특이성IgG （sIgG）수평，병분석불동성별、년령환인적불내수양성솔급불내수식물적분포차이。결과58례환인식물 sIgG 양성솔위84．5％，고우대조조적13．0％，비교차이유통계학의의（P＜0．01）。HSP환인불내수적식물전4위의차위：계단/단백단황（70．7％）、우내（53．4％）、설어（19．0％）、방해（10．3％）；기중1충식물sIgG양성18례（31．0％），2충혹2충이상식물sIgG양성31례（53．4％）。불동성별、불동년령[저령인동（＜7세）급고령인동（≥7세）]식물sIgG총양성솔비교차이무통계학의의（P＞0．05），고령인동적방해IgG양성솔교저령인동고（P＜0．01）。결론HSP환인식물불내수정황교정상인동명현。해조HSP환인대계단/단백단황、우내、설어、방해불내수정황교위명현，가작위지구삼고，고령인동대방해적불내수정황교저령인동명현。
Objective To study food hypersensitivity of children with Hennch-Sehonlein purpura (HSP).Methods The enzyme-linked immunosorbent assay (ELISA)was used to detect 1 4 kinds of food allergen-specific IgG (sIgG)levels in 58 children with HSP and 23 healthy children.Results Eighty-four point five percent(49/58)children with HSP showed food allergen-specific IgG positive(84.5%)higher than healthy children(1 3.0%)(P<0.05).Egg(70.7%),milk(53.4%),codfish(1 9.0%)and crab(1 0.3%) were the main allergens in HSP.Eighteen cases (31 .0%)with HSP were found to have one type of food aller-gen-specific lgG increment,31 cases (53.4%)with two or more types of sIgG increment.The total positive rate of food sIgG showed no difference between sex and age groups (P>0.05).There was higher positive rate of crab IgG in the older children(≥7 years old)(P<0.05).Conclusions Food hypersensitivity of children with HSP is more obvious than healthy children.The mainly allergens of these children were egg,milk,cod-fish and crab,which could be regarded as region refernce.The older children is more sensitive to crab.