CAJ | 학술논문

目的：探讨CEA、CA199、CA724、CA242、CA125、CA50对胰腺癌、结肠癌、胃癌、胆囊癌等消化道肿瘤的诊断价值。方法采用电化学方法及EIA法，检测648例消化道肿瘤患者的CEA、CA199、CA724、CA242、CA125、CA50水平。结果治疗前467例恶性肿瘤患者中肿瘤标志物总阳性检出率为76．66％，高于良性肿瘤患者的39．23％。治疗后235例肿瘤标志物假阳性检出患者肿瘤复发率，高于肿瘤标志物阴性检出患者的31．24％，P＜0．05，有统计学意义。结论 CEA、CA199、CA724、CA242、CA125、CA50在恶性肿瘤中检出率较高，并对判断假阳性检出患者复发有一定意义。
목적：탐토CEA、CA199、CA724、CA242、CA125、CA50대이선암、결장암、위암、담낭암등소화도종류적진단개치。방법채용전화학방법급EIA법，검측648례소화도종류환자적CEA、CA199、CA724、CA242、CA125、CA50수평。결과치료전467례악성종류환자중종류표지물총양성검출솔위76．66％，고우량성종류환자적39．23％。치료후235례종류표지물가양성검출환자종류복발솔，고우종류표지물음성검출환자적31．24％，P＜0．05，유통계학의의。결론 CEA、CA199、CA724、CA242、CA125、CA50재악성종류중검출솔교고，병대판단가양성검출환자복발유일정의의。
Objective To study the diagnostic value of CEA、CA199、CA724、CA242、CA125 and CA50 in gastrointesti-nal tumor such as spancreatic cancer ,colon cancer,gastric cancer and gallbladder carcinoma .Methods CEA、CA199、CA724、CA242、CA125 and CA50 of 648 cases of patients with gastrointestinal tumors were detected .Results Before treatment ,total pos-itive detection rate of tumor markers for malignant tumor patients was 76.66%,which was significantly higher than that of benign tumor patients(39.23%).Recurrence rates of 235 patients with false positive detection of tumor markers were higher than pa-tients with negative detection (31.24%),it had statistical significance,P<0.05.Conclusion CEA、CA199、CA724、CA242、CA125 and CA50 have high detection rate in malignant tumors ,and they have predictive value on the recurrence of recovered pa-tients with false positive detection .