CAJ | 학술논문

目的：探讨连续性血液滤过治疗横纹肌溶解症致急性肾损伤（akiacutekidneyinjury，AKI）患者的效果及总结护理经验。方法对10例横纹肌溶解症致AKI患者采用连续性血液滤过治疗及相应的护理措施。结果经过治疗，10例患者中有7例肾功能恢复正常，治愈出院；2例病情好转出院；1例需要长期维持性血液透析治疗。治疗后患者血清肌酸磷酸激酶（creatine phosphate kinase，CPK）、肌红蛋白（myoglobin，Mb）、尿素氮（urea nitrogen，BUN）、肌酐（creatinine，Scr）、天门冬氨酸氨基转移酶（aspartate amino transferase，AST）浓度逐渐下降，血K+恢复至正常水平，尿量逐渐增多恢复至正常，治疗前后比较，均P＜0.05，差异具有统计学意义。结论连续性血液滤过治疗及相应的护理对保证连续性血液滤过治疗的效果，改善横纹肌溶解症预后有着重要意义。
목적：탐토련속성혈액려과치료횡문기용해증치급성신손상（akiacutekidneyinjury，AKI）환자적효과급총결호리경험。방법대10례횡문기용해증치AKI환자채용련속성혈액려과치료급상응적호리조시。결과경과치료，10례환자중유7례신공능회복정상，치유출원；2례병정호전출원；1례수요장기유지성혈액투석치료。치료후환자혈청기산린산격매（creatine phosphate kinase，CPK）、기홍단백（myoglobin，Mb）、뇨소담（urea nitrogen，BUN）、기항（creatinine，Scr）、천문동안산안기전이매（aspartate amino transferase，AST）농도축점하강，혈K+회복지정상수평，뇨량축점증다회복지정상，치료전후비교，균P＜0.05，차이구유통계학의의。결론련속성혈액려과치료급상응적호리대보증련속성혈액려과치료적효과，개선횡문기용해증예후유착중요의의。
Objective To investigate the effect of continuous hemofiltration in patients with acute renal injury induced by rhabdomyolysis and summarize the nursing experience.Methods Ten patients with acute kidney injury induced by rhabdomyolysis were managed with continuous hemofiltration,corresponding nursing care performed.Results After treatment,the renal function of 7 patients resumed normal,the function of 2 were improved,and only 1 needed long-term hemodialysis.After treatment,the levels of serum creatine phosphokinase(CPK),myoglobin(Mb),blood urea nitrogen(BUN),creatinine(Scr),aspartate aminotransferase(AST) were gradually decreased,K+resumed normal and urine volume increased to normal level,with significant difference as compared to those before treatment(P<0.05).Conclusions Continuous hemofiltration together with pertinent nursing measures can ensure the curative effect.It is of great significance for improving the prognosis of rhabdomyolysis.