CAJ | 학술논문

目的：观察肝癌患者在立体定向放射治疗（stereotactic body radiation therapy，SBRT）不良反应的观察及护理要点。方法2010年7月～2012年5月对本院收治的41例中晚期肝癌患者实施SBRT，治疗期间密切观察患者放疗期间不良反应，并给予相应的护理。结果治疗有效率为56.1%。治疗过程发生1～2级恶心/呕吐36例（87.8%）；1～3级肝酶升高18例（43.9%）；1～2级白细胞下降16例（39.0%），1级贫血8例（19.5%），1～2级血小板下降21例（51.2%），经过治疗护理后患者不良反应均得到有效控制。结论 SBRT是治疗中晚期肝癌的有效方案。治疗过程密切观察患者并发症发生情况，及时采取针对性护理对策，防止并发症进展，特别警惕放射性肝损伤的发生。
목적：관찰간암환자재입체정향방사치료（stereotactic body radiation therapy，SBRT）불량반응적관찰급호리요점。방법2010년7월～2012년5월대본원수치적41례중만기간암환자실시SBRT，치료기간밀절관찰환자방료기간불량반응，병급여상응적호리。결과치료유효솔위56.1%。치료과정발생1～2급악심/구토36례（87.8%）；1～3급간매승고18례（43.9%）；1～2급백세포하강16례（39.0%），1급빈혈8례（19.5%），1～2급혈소판하강21례（51.2%），경과치료호리후환자불량반응균득도유효공제。결론 SBRT시치료중만기간암적유효방안。치료과정밀절관찰환자병발증발생정황，급시채취침대성호리대책，방지병발증진전，특별경척방사성간손상적발생。
Objective To investigate the adverse reactions by stereotactic body radiation therapy(SBRT)for advanced hepatocellular carcinoma and summarize nursing experience.Methods Forty-one patients with advanced hepatocellular carcinoma from the radiation department of Sun Yat-sen University Cancer Center from July 2010 to May 2012 were enrolled in this retrospective study.The adverse reactions were closely observed and the patients were given pertinent nursing.Results The effectiveness rate was 56.2%.During the therapy,36 patients developed nausea/vomiting of grade 1-2,taking up 87.8%,18 had grade 1-3 elevation of liver enzymes,taking up 43.9%,16 had grade 1-2 decrease of white blood cells,taking up 39.0%,8 had grade 1 anemia,taking up 19.5%and 21 had grade 1-2 decrease of blood platelet,taking up 51.2%.The adverse reactions were contained satisfactorily through careful observations and pertinent nursing.Conclusions The toxic reactions by SBRT are nausea,vomiting,enzymes elevation and decrease of whole blood cell.Therefore,nurses need to observe these toxic reactions carefully and give pertinent care to the patients so as to prevent the complications,especially radiation-induced liver injury.