CAJ | 학술논문

目的：了解潍坊地区近年肾脏疾病的病理类型及其与临床表现之间的联系。方法对我院149例肾脏病患者的肾穿刺活检组织标本病理切片分别进行不同染色，行光镜及免疫荧光病理观察。结果本组患者的平均年龄（40．06±13．65）岁，41～50岁为肾脏病的高发年龄段，男女比例为1．44∶1。临床表现以肾病综合征最多见（43．62％），其次为慢性肾小球肾炎（33．55％）。病理类型依次为膜性肾病33．56％，IgA肾病30．87％；继发性肾小球肾炎8．05％，继发性肾小球疾病以狼疮性肾炎最常见，慢性肾功能不全占6．71％．结论潍坊地区最常见的肾脏疾病是原发性肾小球疾病，肾病综合征为最常见的临床表现，肾脏病病理类型中膜性肾病最多见，男性多于女性，发病年龄以中年和青壮年多见。
목적：료해유방지구근년신장질병적병리류형급기여림상표현지간적련계。방법대아원149례신장병환자적신천자활검조직표본병리절편분별진행불동염색，행광경급면역형광병리관찰。결과본조환자적평균년령（40．06±13．65）세，41～50세위신장병적고발년령단，남녀비례위1．44∶1。림상표현이신병종합정최다견（43．62％），기차위만성신소구신염（33．55％）。병리류형의차위막성신병33．56％，IgA신병30．87％；계발성신소구신염8．05％，계발성신소구질병이랑창성신염최상견，만성신공능불전점6．71％．결론유방지구최상견적신장질병시원발성신소구질병，신병종합정위최상견적림상표현，신장병병리류형중막성신병최다견，남성다우녀성，발병년령이중년화청장년다견。
Objective To investigate the correlation between pathology type and clinical manifestations of kidney diseases among 149 cases 2 years recently in our hospital.Methods One hundred and forty-nine cases samples were disposed regularly in pathological department ,cut into slides and stained with several methods .The results were ob-served under the light microscope and the fluorescence microscope .Results In this group,the mean age was 40.06 ± 13.65.Notably,the kidney diseases were most likely to occur between 31 and 50 years old.Of clinical manifestations,ne-phrotic syndrome(43.62%) was most commonly seen,followed by urinary abnormalities(33.55%).The pathology types of nephrotic syndrome were membranous nephropathy (33.56%) and IgA nephropathy (30.87%).On other hand,the occurrence rate of secondary glomerulonephritis was 10.07%.Notably,lupus nephritis was the most commonly found . Chronic renal insufficiency was 6.71%.Conclusions Primary glomerular disease is the most common kidney disease , and nephrotic syndrome is the most common clinical manifestation in Weifang area .The most common kidney pathologi-cal types in membranous nephropathy ,male is more than Female.The middle-aged and young adults are high-risk popu-lations.