北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2014年
3期
47-47,48
,共2页
葡萄籽%软胶囊%正交试验%填充物
葡萄籽%軟膠囊%正交試驗%填充物
포도자%연효낭%정교시험%전충물
Grape Soft capsule%Orthogonal design%Content
以大豆油为分散介质,蜂蜡为助悬剂,大豆磷脂为润湿剂,以沉降比和再分散性为指标,采用正交设计优化葡萄籽软胶囊的填充物处方。结果表明:葡萄籽软胶囊的填充物最佳配比为葡萄籽提取物-大豆油-蜂蜡-大豆磷脂(18.2∶72.8∶6∶3),制备得到的软胶囊填充物料液均匀、稳定、流动性好。
以大豆油為分散介質,蜂蠟為助懸劑,大豆燐脂為潤濕劑,以沉降比和再分散性為指標,採用正交設計優化葡萄籽軟膠囊的填充物處方。結果錶明:葡萄籽軟膠囊的填充物最佳配比為葡萄籽提取物-大豆油-蜂蠟-大豆燐脂(18.2∶72.8∶6∶3),製備得到的軟膠囊填充物料液均勻、穩定、流動性好。
이대두유위분산개질,봉사위조현제,대두린지위윤습제,이침강비화재분산성위지표,채용정교설계우화포도자연효낭적전충물처방。결과표명:포도자연효낭적전충물최가배비위포도자제취물-대두유-봉사-대두린지(18.2∶72.8∶6∶3),제비득도적연효낭전충물료액균균、은정、류동성호。
The preparation of Grape Seed Extract Soft Capsule was optimized by orthogonal design with evaluation indexes such as sedimentation ratio and redispersibility,by taking soybean oil as the disperse medium, beeswax as the suspending agent, and soybean phospholipid as the moistening agent. The results showed that the optimal proportion of soft capsule contents were made from Grape Seed Extract. soybean oil. beeswax and soybean phospholipid (18.2∶72.8∶6∶3)and the contents of soft capsule were well distributed with good stabilization and fluidity.