CAJ | 학술논문

目的：讨论盐酸贝那普利在辅助早期糖尿病肾病治疗中的临床疗效。方法回顾性分析2012年4月至2013年4月期间因糖尿病并发早期肾病入住我院治疗患者112例，按计划分为2组，每组各56例，分别予以盐酸贝那普利和阿托伐他汀进行辅助治疗，比较2组患者用药后2周后实验室指标和临床疗效。结果盐酸贝那普利组治疗后尿素氮（BUN）（6.08±2.01）mmol/L明显低于阿托伐他汀组（8.01±2.89）mmol/L，肌酐清除率（Cr）（113.22±12.99）μmol/L明显高于阿托伐他汀组（95.3±12.47）μmol/L，显效率83.9%显著高于阿托伐他汀组69.7%。结论盐酸贝那普利辅助治疗早期糖尿病肾病有效改善肾功能各项指标，临床疗效好，推荐临床广泛应用。
목적：토론염산패나보리재보조조기당뇨병신병치료중적림상료효。방법회고성분석2012년4월지2013년4월기간인당뇨병병발조기신병입주아원치료환자112례，안계화분위2조，매조각56례，분별여이염산패나보리화아탁벌타정진행보조치료，비교2조환자용약후2주후실험실지표화림상료효。결과염산패나보리조치료후뇨소담（BUN）（6.08±2.01）mmol/L명현저우아탁벌타정조（8.01±2.89）mmol/L，기항청제솔（Cr）（113.22±12.99）μmol/L명현고우아탁벌타정조（95.3±12.47）μmol/L，현효솔83.9%현저고우아탁벌타정조69.7%。결론염산패나보리보조치료조기당뇨병신병유효개선신공능각항지표，림상료효호，추천림상엄범응용。
Objective To discuss the clinical effect of benazepril hydrochloride in assisting treatment for EDN. Method 112 cases of EDN were retrospectively analyzed and divided into 2 groups both with 56 cases. The 2 groups were given respectively enazepril hydrochloride and atorvastatin for assisted treatment. Laboratory indicators and clinical effects of the 2 groups after 2 weeks of medication treatment were compared. Result After treatment, BUN of enazepril hydrochloride group was (6.08±2.01)mmol/L obviously lower than atorvastatin group (8.01±2.89)mmol/L, Cr was (113.22± 12.99)μmol/L obviously higher than atorvastatin group (95.3±12.47)μmol/L. Effective rate was 83.9%obviously higher than atorvastatin group 69.7%. Conclusion Benazepril hydrochloride in assisting treatment for EDN can effectively improve each indicators of kidney function. It has good clinical effect and is worth of being popularized in clinical work.