CAJ | 학술논문

目的：分析探讨非老年患者上消化道出血的原因及相关因素。方法对我院2009年~2012年间收治的135例非老年上消化道出血患者的临床资料进行回顾性分析，并与同期住院86例老年患者的出血原因进行比较。结果在135例非老年上消化道出血病例中，饮酒、精神因素、不当饮食为主要相关诱发因素，老年组中以服用非甾体药物为主要诱因。而非老年组中最常见的出血病因为十二指肠溃疡占34.81%(47/135)，第二位是食管胃底静脉曲张破裂占18.52%(25/135)，其他常见的病因还有急性胃黏膜病变15.56%(21/135)，胃溃疡11.58%(16/135)，消化道肿瘤7.41%(10/135)等。其中十二指肠溃疡、食管胃底静脉曲张发病率明显高于老年组，而胃溃疡、消化道肿瘤发病率低于老年组患者(P＜0.05)。结论与老年组有所不同，非老年上消化道出血诱因多与饮酒、精神因素、不当饮食有关，十二指肠溃疡、食管胃底黏膜曲张破裂是致出血的主要病因，且发病率男性多于女性。
목적：분석탐토비노년환자상소화도출혈적원인급상관인소。방법대아원2009년~2012년간수치적135례비노년상소화도출혈환자적림상자료진행회고성분석，병여동기주원86례노년환자적출혈원인진행비교。결과재135례비노년상소화도출혈병례중，음주、정신인소、불당음식위주요상관유발인소，노년조중이복용비치체약물위주요유인。이비노년조중최상견적출혈병인위십이지장궤양점34.81%(47/135)，제이위시식관위저정맥곡장파렬점18.52%(25/135)，기타상견적병인환유급성위점막병변15.56%(21/135)，위궤양11.58%(16/135)，소화도종류7.41%(10/135)등。기중십이지장궤양、식관위저정맥곡장발병솔명현고우노년조，이위궤양、소화도종류발병솔저우노년조환자(P＜0.05)。결론여노년조유소불동，비노년상소화도출혈유인다여음주、정신인소、불당음식유관，십이지장궤양、식관위저점막곡장파렬시치출혈적주요병인，차발병솔남성다우녀성。
Objective To investigate the cause of upper gastrointestinal bleeding and relevant factors in non elderly patients. Methods Clinical data of 135 non elderly patients with upper gastrointestinal bleeding during 2009 and 2012 in our hospital and 86 cases of elderly patients at the same period were retrospectively analyzed. The causes of acute gastrointestinal bleeding were compared. Results Drinking wines, mental factors and improper diets in non elderly patients were main inducements leading to gastrointestinal hemorrhage. The inducement of the elderly group was NSAID drug. The most common cause of gastrointestinal hemorrhage in the non elderly group was the duodenal ulcer accounted for 34.81%(47/135), the second was the esophageal gastric fundus varicosity burst accounted for 18.82%(25/135). Other causes were acute gastric mucosal lesion 15.56%(21/135), gastric ulcer 11.58%(16/135) and the digestive tract cancer 7.41%(10/135) etc. The incidence of the duodenal ulcer and the esophageal gastric fundus varicosity burst were significantly higher than the elderly group, the incidence of gastric ulcer and the digestive tract cancer in turn were significantly lower than the elderly group (P<0.05). Conclusion Compared with the elderly group, the inducements of the non elderly group were related to drinking wines, mental factors and improper diets. The duodenal ulcer and the esophageal gastric fundus varicosity burst were accounted for main two causes of acute upper gastrointestinal bleeding and the ratio is higher in males than in females.