CAJ | 학술논문

目的：探讨西咪替丁联合潘生丁治疗过敏性紫癜的临床疗效。方法将在我院2012年6月至2013年6月收治的过敏性紫癜86例患者，随机分为观察组和对照组，观察组给予西咪替丁联合潘生丁治疗，对照组给予泼尼松、维生素C、维生素D、钙剂、氯雷他定治疗。比较两组患者临床疗效及不良反应的发生情况。结果观察组总有效率93.02%，对照组有效率79.07%，两组总有效率具有差异性（P<0.05）。且观察组患者皮肤紫癜消退时间，临床症状消失时间，住院天数均明显低于对照组，两组相比具有差异性（P<0.05），西咪替丁联合潘生丁也无明显不良反应。结论西米替西联合潘生丁治疗过敏性紫癜疗效显着，且无严重不良反应，使用便利，患者依从性好，值得临床广泛推广和使用。
목적：탐토서미체정연합반생정치료과민성자전적림상료효。방법장재아원2012년6월지2013년6월수치적과민성자전86례환자，수궤분위관찰조화대조조，관찰조급여서미체정연합반생정치료，대조조급여발니송、유생소C、유생소D、개제、록뢰타정치료。비교량조환자림상료효급불량반응적발생정황。결과관찰조총유효솔93.02%，대조조유효솔79.07%，량조총유효솔구유차이성（P<0.05）。차관찰조환자피부자전소퇴시간，림상증상소실시간，주원천수균명현저우대조조，량조상비구유차이성（P<0.05），서미체정연합반생정야무명현불량반응。결론서미체서연합반생정치료과민성자전료효현착，차무엄중불량반응，사용편리，환자의종성호，치득림상엄범추엄화사용。
Objective The discussion cimetidine and dipyridamole combination to treat the allergic purpura the clinical curative effect. Methods The method the allergic purpura 86 example patients who from June 2012 to June 2013 will admit in my courtyard, will divide into the observation group and the control group stochastically, the observation group gives the cimetidine and dipyridamole combination to treat, the control group will give prednisone, vitamin C, vitamin D, the calcium medicinal preparation, the loratadine. Two groups were compared the clinical efficacy and adverse reactions. Results Finally observation group total effectiveness 93.02%, control group effectiveness 79.07%, two groups of total effectiveness have the difference (P<0.05). Also the observation group patient skin purpura retrogression time, the clinical symptom vanishing time, in hospital number of days obviously is lower than the control group, two groups compare have the difference (P<0.05), the cimetidine and dipyridamole combination to treat patients also not obviously not good to respond.Conclusion The conclusion cimetidine and dipyridamole combination to treat the allergic purpura curative effect to be remarkable, also no serious adverse reactions, the use convenience, the patient complies is good, is worth the clinical widespread promotion and the use.