中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
9期
1374-1379
,共6页
毕中普%夏磊%徐静磊%周亚旗%柯广水%桑亮
畢中普%夏磊%徐靜磊%週亞旂%柯廣水%桑亮
필중보%하뢰%서정뢰%주아기%가엄수%상량
植入物%脊柱植入物%脊柱侧弯%钉棒内固定%特发性%手术%相关因素
植入物%脊柱植入物%脊柱側彎%釘棒內固定%特髮性%手術%相關因素
식입물%척주식입물%척주측만%정봉내고정%특발성%수술%상관인소
spine%spinal curvatures%scoliosis%internal fixators%bone nails%orthotic devices
背景：特发性脊柱侧弯在脊柱侧弯中最常见，有时还伴有神经、内分泌系统以及营养代谢的异常，但保守治疗效果欠佳，通常需要进行手术治疗。畸形矫正是一个极其复杂的过程，对特发性脊柱侧弯治疗、转归等进行深入研究意义巨大，但目前缺少相近研究。<br> 目的：观察后路钉棒内固定置入治疗特发性脊柱侧弯的矫正效果，探讨影响其效果的相关因素。<br> 方法：回顾性分析近4年80例接受后路钉棒内固定置入治疗的特发性脊柱侧弯患者的病例资料，记录研究患者年龄、性别、病程、治疗前后X射线平片测量的冠状面Cobb's角、躯干偏移度等观察指标，并进行统计学分析。<br> 结果与结论：单因素分析显示患者性别和患者病程均与内固定后矫正效果无明显相关(P>0.05)；而患者年龄分布、侧凸的位置、侧凸的柔韧性均与内固定疗效相关(P<0.05)。后路钉棒内固定治疗特发性脊柱侧弯可以获得明显的矫正效果，患者的年龄、侧凸的位置、侧凸的柔韧性等对内固定效果有明显的影响，患者的性别和病程对内固定效果无明显影响。
揹景：特髮性脊柱側彎在脊柱側彎中最常見，有時還伴有神經、內分泌繫統以及營養代謝的異常，但保守治療效果欠佳，通常需要進行手術治療。畸形矯正是一箇極其複雜的過程，對特髮性脊柱側彎治療、轉歸等進行深入研究意義巨大，但目前缺少相近研究。<br> 目的：觀察後路釘棒內固定置入治療特髮性脊柱側彎的矯正效果，探討影響其效果的相關因素。<br> 方法：迴顧性分析近4年80例接受後路釘棒內固定置入治療的特髮性脊柱側彎患者的病例資料，記錄研究患者年齡、性彆、病程、治療前後X射線平片測量的冠狀麵Cobb's角、軀榦偏移度等觀察指標，併進行統計學分析。<br> 結果與結論：單因素分析顯示患者性彆和患者病程均與內固定後矯正效果無明顯相關(P>0.05)；而患者年齡分佈、側凸的位置、側凸的柔韌性均與內固定療效相關(P<0.05)。後路釘棒內固定治療特髮性脊柱側彎可以穫得明顯的矯正效果，患者的年齡、側凸的位置、側凸的柔韌性等對內固定效果有明顯的影響，患者的性彆和病程對內固定效果無明顯影響。
배경：특발성척주측만재척주측만중최상견，유시환반유신경、내분비계통이급영양대사적이상，단보수치료효과흠가，통상수요진행수술치료。기형교정시일개겁기복잡적과정，대특발성척주측만치료、전귀등진행심입연구의의거대，단목전결소상근연구。<br> 목적：관찰후로정봉내고정치입치료특발성척주측만적교정효과，탐토영향기효과적상관인소。<br> 방법：회고성분석근4년80례접수후로정봉내고정치입치료적특발성척주측만환자적병례자료，기록연구환자년령、성별、병정、치료전후X사선평편측량적관상면Cobb's각、구간편이도등관찰지표，병진행통계학분석。<br> 결과여결론：단인소분석현시환자성별화환자병정균여내고정후교정효과무명현상관(P>0.05)；이환자년령분포、측철적위치、측철적유인성균여내고정료효상관(P<0.05)。후로정봉내고정치료특발성척주측만가이획득명현적교정효과，환자적년령、측철적위치、측철적유인성등대내고정효과유명현적영향，환자적성별화병정대내고정효과무명현영향。
BACKGROUND:Idiopathic scoliosis is most common among al the scoliosis. Accompanied by the nervous system, the endocrine system as wel as nutritional and metabolic abnormalities, patients usual y cannot be redressed and cured by conservative treatment, but often require surgical operation. Surgery for malformation is a very complicated project, and is real y of great significance for an in-depth research on treatment and turnover of idiopathic scoliosis. <br> OBJECTIVE:To observe the correction effect of posterior screw-rod fixation for idiopathic scoliosis, and explore the relevant factors influencing its effectiveness. <br> METHODS:We retrospectively analyzed 80 cases receiving pedicle screw fixation in the treatment of idiopathic scoliosis in the latest four years. Age, gender, disease duration, preoperative and postoperative X-ray measurement of coronal Cobb’s angle, and trunk deviation were recorded, and statistical y analyzed. <br> RESULTS AND CONCLUSION:Univariate analysis showed that gender and disease duration were not significantly correlated with postoperative correction results (P>0.05). However, the age distribution of patients, the location of scoliosis, and scoliosis flexibility were associated with curative effects of internal fixation (P<0.05). Posterior screw-rod fixation for idiopathic scoliosis can achieve significant effects. The patient’s age, location and flexibility of scoliosis have a significant effect on the effects of fixation. The patient’s gender and disease duration had no significant effect on fixation effects.
