CAJ | 학술논문

Claudin-1蛋白是一种闭合蛋白，也是细胞间紧密连接蛋白的主要组成部分，其特异性的组织表达，在保持紧密连接屏障功能和细胞极性方面具有重要作用。表达异常的Clandin-1蛋白与上皮性卵巢癌的转移和侵袭密切相关，本文综述了Claudin-1与卵巢癌相关性的研究进展。
Claudin-1단백시일충폐합단백，야시세포간긴밀련접단백적주요조성부분，기특이성적조직표체，재보지긴밀련접병장공능화세포겁성방면구유중요작용。표체이상적Clandin-1단백여상피성란소암적전이화침습밀절상관，본문종술료Claudin-1여란소암상관성적연구진전。
Claudin-1 is a family of integral membrane tight junction ( TJ ) proteins. The tissue-specific expressions of claudin-1 proteins perform specialized epithelial or endothelial functions including maintenance of ceil polarity and paracellular barrier functions. Many researches indicate that abnormal expression of claudin-1 has a relationship with the invasion and metastasis of ovarian cancer. This article reviewed the relationship of Claudin-1 and ovarian cancer.