西部中医药
西部中醫藥
서부중의약
GANSU JOURNAL OF TRADITIONAL CHINESE MEDICINE
2014年
6期
78-79
,共2页
心力衰竭,慢性%辨证论治%安全性
心力衰竭,慢性%辨證論治%安全性
심력쇠갈,만성%변증론치%안전성
heart failure,chronic%syndrome differentiation and patterns%the safety
目的：观察辨证论治慢性心力衰竭的临床疗效。方法：将180例患者随机分为3组，每组60例，3组患者均给予西医常规治疗。气虚血瘀组加用保元汤合补阳还五汤加减治疗，阳虚水泛组加用真武汤加味治疗。比较3组临床疗效及左室射血分数(LVEF)、左室短轴缩短率(FS)、肿瘤坏死因子(TNF-α)、血管紧张素Ⅱ(Ang-Ⅱ)、白细胞介素-6(IL-6)等指标的变化。结果：气虚血瘀组、阳虚水泛组总有效率均高于对照组(P＜0.05)；LVEF、FS 3组治疗后均较治疗前有明显提高（P＜0.05），气虚血瘀组、阳虚水泛组与对照组相比，差异具有统计学意义（P＜0.05）；3组治疗后Ang-Ⅱ、IL-6及TNF-α显著降低（P＜0.05）。结论：辨证论治疗慢性心力衰竭临床疗效显著。
目的：觀察辨證論治慢性心力衰竭的臨床療效。方法：將180例患者隨機分為3組，每組60例，3組患者均給予西醫常規治療。氣虛血瘀組加用保元湯閤補暘還五湯加減治療，暘虛水汎組加用真武湯加味治療。比較3組臨床療效及左室射血分數(LVEF)、左室短軸縮短率(FS)、腫瘤壞死因子(TNF-α)、血管緊張素Ⅱ(Ang-Ⅱ)、白細胞介素-6(IL-6)等指標的變化。結果：氣虛血瘀組、暘虛水汎組總有效率均高于對照組(P＜0.05)；LVEF、FS 3組治療後均較治療前有明顯提高（P＜0.05），氣虛血瘀組、暘虛水汎組與對照組相比，差異具有統計學意義（P＜0.05）；3組治療後Ang-Ⅱ、IL-6及TNF-α顯著降低（P＜0.05）。結論：辨證論治療慢性心力衰竭臨床療效顯著。
목적：관찰변증론치만성심력쇠갈적림상료효。방법：장180례환자수궤분위3조，매조60례，3조환자균급여서의상규치료。기허혈어조가용보원탕합보양환오탕가감치료，양허수범조가용진무탕가미치료。비교3조림상료효급좌실사혈분수(LVEF)、좌실단축축단솔(FS)、종류배사인자(TNF-α)、혈관긴장소Ⅱ(Ang-Ⅱ)、백세포개소-6(IL-6)등지표적변화。결과：기허혈어조、양허수범조총유효솔균고우대조조(P＜0.05)；LVEF、FS 3조치료후균교치료전유명현제고（P＜0.05），기허혈어조、양허수범조여대조조상비，차이구유통계학의의（P＜0.05）；3조치료후Ang-Ⅱ、IL-6급TNF-α현저강저（P＜0.05）。결론：변증론치료만성심력쇠갈림상료효현저。
Objective: To observe therapeutic effects of syndrome differentiation and treatment in treating chronic heart failure(CHF). Methods:All 180 patients were randomly divided into three groups, 60 cases each group, all the patients received conventional therapy of western medicine. Qi-insufficiency blood-stasis group took BaoYuan Tang and modified BuYang HuanWu Tang, Yang-deficiency water-flooding group received modified ZhenWu Tang. The changes of LVEF, FS, TNF-α, Ang-Ⅱand IL-6 of three groups were compared as well as therapeutic effects. Results:Total effective rates of Qi-insufficiency blood-stasis group and Yang-deficiency water-flooding group were higher than that of the control group (P<0.05);LVEF and FS of three groups after treating were improved signifi-cantly compared with before treating (P<0.05), the differences had statistical meaning when Qi-insufficiency blood-stasis group and Yang-deficiency water-flooding group were compared with the control group (P<0.05);Ang-Ⅱ, IL-6 and TNF-αof three groups after treating were decreased (P<0.05). Conclusion:Treating CHF by syndrome differentiation and treatment is effective.
