西部中医药
西部中醫藥
서부중의약
GANSU JOURNAL OF TRADITIONAL CHINESE MEDICINE
2014年
6期
4-6
,共3页
中晚期膀胱癌%化疗灌注%益气活血汤%生存质量%免疫
中晚期膀胱癌%化療灌註%益氣活血湯%生存質量%免疫
중만기방광암%화료관주%익기활혈탕%생존질량%면역
bladder cancer at moderate and advanced stages%irrigation chemotherapy%Qi-invigorating and blood-activating decoction%life quality%immunity
目的：探讨化疗灌注结合益气活血汤在中晚期膀胱癌治疗中的效果。方法：将180例中晚期膀胱癌患者随机分为治疗组与对照组各90例，所有患者均给予双侧髂内动脉化疗灌注治疗，在此基础上治疗组加用益气活血汤口服治疗。结果：所有患者治疗后出院，治疗组的心理、独立性、社会关系和环境维度评分明显高于对照组(P＜0.05)。治疗组的1年生存率为98.9%，对照组为91.1%，组间对比差异有统计学意义(P＜0.05)。2组治疗前CD4+、CD8+、NK细胞值对比差异无统计学意义，治疗后治疗组的CD4+与NK细胞值明显上升(P＜0.05)， CD8+值明显下降，组间对比有统计学意义(P＜0.05)。结论：化疗灌注结合益气活血汤应用于中晚期膀胱癌的治疗能促进患者康复，提高患者生存率，这可能与有效改善免疫状态有关。
目的：探討化療灌註結閤益氣活血湯在中晚期膀胱癌治療中的效果。方法：將180例中晚期膀胱癌患者隨機分為治療組與對照組各90例，所有患者均給予雙側髂內動脈化療灌註治療，在此基礎上治療組加用益氣活血湯口服治療。結果：所有患者治療後齣院，治療組的心理、獨立性、社會關繫和環境維度評分明顯高于對照組(P＜0.05)。治療組的1年生存率為98.9%，對照組為91.1%，組間對比差異有統計學意義(P＜0.05)。2組治療前CD4+、CD8+、NK細胞值對比差異無統計學意義，治療後治療組的CD4+與NK細胞值明顯上升(P＜0.05)， CD8+值明顯下降，組間對比有統計學意義(P＜0.05)。結論：化療灌註結閤益氣活血湯應用于中晚期膀胱癌的治療能促進患者康複，提高患者生存率，這可能與有效改善免疫狀態有關。
목적：탐토화료관주결합익기활혈탕재중만기방광암치료중적효과。방법：장180례중만기방광암환자수궤분위치료조여대조조각90례，소유환자균급여쌍측가내동맥화료관주치료，재차기출상치료조가용익기활혈탕구복치료。결과：소유환자치료후출원，치료조적심리、독립성、사회관계화배경유도평분명현고우대조조(P＜0.05)。치료조적1년생존솔위98.9%，대조조위91.1%，조간대비차이유통계학의의(P＜0.05)。2조치료전CD4+、CD8+、NK세포치대비차이무통계학의의，치료후치료조적CD4+여NK세포치명현상승(P＜0.05)， CD8+치명현하강，조간대비유통계학의의(P＜0.05)。결론：화료관주결합익기활혈탕응용우중만기방광암적치료능촉진환자강복，제고환자생존솔，저가능여유효개선면역상태유관。
Objective: To explore the effects of irrigation chemotherapy combined with Qi-invigorating and blood-activating decoction in treating bladder cancer at moderate and advanced stages. Methods: All 180 patients were randomly separated into the treatment group and the control group, 90 cases each group. All the patients were administered with internal iliac artery irrigation chemotherapy bilaterally, the treatment group took Qi-invigorating and blood-activating decoction. Results:When all the patients were discharged, the treatment group was significantly higher than the control group in the psychology, independence, social relationship and the environment (P<0.05). One-year survival rate of the treatment group was 98.9%, higher than 91.1% of the control group, the difference demonstrated statistical meaning (P<0.05). The difference had no statistical meaning before treating in CD4+, CD8+and NK cell values, after treating, CD4+and NK cell values of the treatment group were raised obviously (P<0.05), CD8+was decreased remarkably, the comparison between both groups presented statistical meaning (P<0.05). Con-clusion:Irrigation chemotherapy combined with Qi-invigorating and blood-activating decoction applied to bladder cancer at moderate and advanced stages could promote the recovery of the patients, lift survival rate of the patients, which might be related to effective improvement of immunity.
