陕西医学杂志
陝西醫學雜誌
협서의학잡지
SHAANXI MEDICAL JOURNAL
2014年
7期
782-784
,共3页
心肺复苏术%潮气末CO2分压%除颤器%血液循环%肺循环%狗
心肺複囌術%潮氣末CO2分壓%除顫器%血液循環%肺循環%狗
심폐복소술%조기말CO2분압%제전기%혈액순배%폐순배%구
Cardiopulmonary resuscitation%End-tidal partial pressure of carbon dioxide%Defibrilla-tors%Blood circulation%Circulation%Dogs
目的：以电击致犬室颤建立的心脏骤停动物模型为研究对象，研究在心肺复苏模式下犬的潮气末二氧化碳分压（PETCO2）的变化。方法：选健康杂种犬36只随机分为三组：4min胸外按压组；4min开胸复苏组；8min开胸复苏组。每组12只犬，雌、雄各半，致颤前及复苏过程中对潮气末二氧化碳分压进行监测。结果：4min胸外按压组PETCO2在复苏前5min时与4min开胸复苏组和8min开胸复苏组比较，差异有统计学意义。在其他时相三组间均无统计学意义。自主循环恢复组与失败组在复苏1min 时就有统计学意义，在复苏20min时，失败组9例 PETCO2均≤13mmHg ，自主循环恢复组27例PETCO2均＞13mmHg ，计算敏感性，特异性，阳性预测值和阴性预测值均是100％。自主循环恢复后与恢复前刻比较，差异有统计学意义。结论：潮气末二氧化碳分压可以在心肺复苏期间预测复苏结果；复苏20min时潮气末二氧化碳分压＞13mmHg时复苏成功率较高。在复苏期间潮气末二氧化碳分压突然上升5mmHg以上可能预示自主循环即刻恢复。
目的：以電擊緻犬室顫建立的心髒驟停動物模型為研究對象，研究在心肺複囌模式下犬的潮氣末二氧化碳分壓（PETCO2）的變化。方法：選健康雜種犬36隻隨機分為三組：4min胸外按壓組；4min開胸複囌組；8min開胸複囌組。每組12隻犬，雌、雄各半，緻顫前及複囌過程中對潮氣末二氧化碳分壓進行鑑測。結果：4min胸外按壓組PETCO2在複囌前5min時與4min開胸複囌組和8min開胸複囌組比較，差異有統計學意義。在其他時相三組間均無統計學意義。自主循環恢複組與失敗組在複囌1min 時就有統計學意義，在複囌20min時，失敗組9例 PETCO2均≤13mmHg ，自主循環恢複組27例PETCO2均＞13mmHg ，計算敏感性，特異性，暘性預測值和陰性預測值均是100％。自主循環恢複後與恢複前刻比較，差異有統計學意義。結論：潮氣末二氧化碳分壓可以在心肺複囌期間預測複囌結果；複囌20min時潮氣末二氧化碳分壓＞13mmHg時複囌成功率較高。在複囌期間潮氣末二氧化碳分壓突然上升5mmHg以上可能預示自主循環即刻恢複。
목적：이전격치견실전건립적심장취정동물모형위연구대상，연구재심폐복소모식하견적조기말이양화탄분압（PETCO2）적변화。방법：선건강잡충견36지수궤분위삼조：4min흉외안압조；4min개흉복소조；8min개흉복소조。매조12지견，자、웅각반，치전전급복소과정중대조기말이양화탄분압진행감측。결과：4min흉외안압조PETCO2재복소전5min시여4min개흉복소조화8min개흉복소조비교，차이유통계학의의。재기타시상삼조간균무통계학의의。자주순배회복조여실패조재복소1min 시취유통계학의의，재복소20min시，실패조9례 PETCO2균≤13mmHg ，자주순배회복조27례PETCO2균＞13mmHg ，계산민감성，특이성，양성예측치화음성예측치균시100％。자주순배회복후여회복전각비교，차이유통계학의의。결론：조기말이양화탄분압가이재심폐복소기간예측복소결과；복소20min시조기말이양화탄분압＞13mmHg시복소성공솔교고。재복소기간조기말이양화탄분압돌연상승5mmHg이상가능예시자주순배즉각회복。
Objective:To study the effects of different types of cardiopulmonary resuscitation (CPR) on the partial pressure of end-tidal carbon dioxide (PETCO2 ) based on the cardiac arrest dog model of ventricular fibril-lation by electric shock .Methods :36 healthy dogs were randomly divided into 3 groups:4 minutes close-chest CPR , 4 minutes open-chest CPR ,and 8 minutes open-chest CPR .There were 12 dogs in each group ,half male and half fe-male .In the process of the CPR ,all parameters about PETCO2 were recorded .Results :Compared with 4 minutes open-chest CPR group and 8 minutes open-chest CPR group ,4 minutes close-chest CPR had a statistically significant difference on PETCO2 in 5 minutes before resuscitation .There was no statistical significance among these three groups in the other time phase .In the first minutes ,statistical significance existed between the success group and failure group .The PETCO2 of 9 cases of failure group were ≤ 13mmHg in 20 minutes of resuscitations ,and the PETCO2 of 27 cases of success group were > 13mmHg .The positive predictive value and negative predictive value were 100% on the consideration of sensitivity and specificity .To compare before and after the resuscitation of spon-taneous circulation ,the difference was statistically significant .Conclusions :PETCO2 parameters can be used to e-valuate the prognosis effects of the CPR .When the PETCO2 are >13mmHg ,the success rate of resuscitations is higher .
