中国实用神经疾病杂志
中國實用神經疾病雜誌
중국실용신경질병잡지
CHINESE JOURNAL OF PRACTICAL NERVOUS DISEASES
2014年
12期
21-23
,共3页
早期介入治疗%颅内动脉瘤破裂%预后
早期介入治療%顱內動脈瘤破裂%預後
조기개입치료%로내동맥류파렬%예후
EIS%RIA%Prognosis
目的：探讨早期介入治疗（Early Invasive Strategy ，EIS）对颅内动脉瘤破裂（Ruptured Intracranial Aneurysm ， RIA ）患者预后的影响。方法选择2011-09-2013-10接诊的RIA患者92例，按照发病时间到治疗时间的不同分为EIS组和晚期介入治疗（LIS）组，每组各46例。EIS组在发病后72 h内接受治疗，而LIS组在发病超过72h后接受治疗。比较2组术后栓塞情况、GOS预后评分和并发症发生情况。结果 EIS组完全栓塞38例（82.6％），大部分栓塞7例，部分栓塞1例， LIS组完全栓塞25例（54.3％），大部分栓塞12例，部分栓塞9例，EIS组栓塞效果明显优于LIS组；EIS组GOS≥4的患者39例（84.8％），LIS组GOS≥4的患者28例（60.9％），EIS组预后明显优于LIS组；EIS组并发症15例（32.6％），LIS组并发症3例（6.5％）；2组差异比较有统计学意义（ P＜0.05）。结论 EIS对RIA的治疗效果显著，能显著减少并发症的发生，保障患者安全，明显提升预后，值得临床推广。
目的：探討早期介入治療（Early Invasive Strategy ，EIS）對顱內動脈瘤破裂（Ruptured Intracranial Aneurysm ， RIA ）患者預後的影響。方法選擇2011-09-2013-10接診的RIA患者92例，按照髮病時間到治療時間的不同分為EIS組和晚期介入治療（LIS）組，每組各46例。EIS組在髮病後72 h內接受治療，而LIS組在髮病超過72h後接受治療。比較2組術後栓塞情況、GOS預後評分和併髮癥髮生情況。結果 EIS組完全栓塞38例（82.6％），大部分栓塞7例，部分栓塞1例， LIS組完全栓塞25例（54.3％），大部分栓塞12例，部分栓塞9例，EIS組栓塞效果明顯優于LIS組；EIS組GOS≥4的患者39例（84.8％），LIS組GOS≥4的患者28例（60.9％），EIS組預後明顯優于LIS組；EIS組併髮癥15例（32.6％），LIS組併髮癥3例（6.5％）；2組差異比較有統計學意義（ P＜0.05）。結論 EIS對RIA的治療效果顯著，能顯著減少併髮癥的髮生，保障患者安全，明顯提升預後，值得臨床推廣。
목적：탐토조기개입치료（Early Invasive Strategy ，EIS）대로내동맥류파렬（Ruptured Intracranial Aneurysm ， RIA ）환자예후적영향。방법선택2011-09-2013-10접진적RIA환자92례，안조발병시간도치료시간적불동분위EIS조화만기개입치료（LIS）조，매조각46례。EIS조재발병후72 h내접수치료，이LIS조재발병초과72h후접수치료。비교2조술후전새정황、GOS예후평분화병발증발생정황。결과 EIS조완전전새38례（82.6％），대부분전새7례，부분전새1례， LIS조완전전새25례（54.3％），대부분전새12례，부분전새9례，EIS조전새효과명현우우LIS조；EIS조GOS≥4적환자39례（84.8％），LIS조GOS≥4적환자28례（60.9％），EIS조예후명현우우LIS조；EIS조병발증15례（32.6％），LIS조병발증3례（6.5％）；2조차이비교유통계학의의（ P＜0.05）。결론 EIS대RIA적치료효과현저，능현저감소병발증적발생，보장환자안전，명현제승예후，치득림상추엄。
Objective To explore the impact of early invasive strategy (EIS)on the prognosis of patients with ruptured in-tracranial aneurysms(RIA).Methods 92 patients with RIA in our hospital from September 2011 to October 2013 were chosen , and divided into two groups ,EIS group and late invasive strategy group (LIS) ,according to the different time of onset to the treatment time ,46 cases in each group. EIS group received treatment within 72 h after the onset ,and LIS group accepted treat-ment after 72 h of the onset. The status of embolization ,GOS prognostic score and complications of the two groups were ob-served and compared. Results 38 cases(82.6% ) were completely embolized ,7 cases were majorly embolized ,and 1 case was partially embolized in EIS group ;25 cases (54.3% ) were completely embolized ,12 cases were majorly embolized ,and 9 cases were partially embolized in LIS group ,embolization efficacy of EIS group was significantly better than that of LIS group ;39 ca-ses had GOS ≥ 4 in EIS group ,accounting for 84.8% ;and 28 cases had GOS ≥ 4 in LIS group ,accounting for 60.9%. The prognosis of EIS group was significantly better than that of the LIS group ;15 cases with complications in EIS group ,accounted for 32.6% ,and 3 patients with complications in LIS group ,accounted for 6.5% ;differences between the above items were sta-tistically significant (P<0.05).Conclusion EIS has a significant effect on the therapy for RIA ,and can significantly reduce the incidence of complications ,ensure the safety of patients ,as well as significantly improve the prognosis ,and thus is worthy of further promotion in clinical practice.
