CAJ | 학술논문

温度敏感型原位凝胶是现在国内外研究新型药物传递系统的一个热点，因具有良好的流动性、较长的滞留时间、高效的生物利用度及良好的控制释药性能等优点成为了新型给药系统的主要研究对象。本文以近年来国内外研究温度敏感型原位凝胶的相关文献，对其基质选择、给药途径及质量控制的研究进行综述，从而为温度敏感型原位凝胶的新型药物研发提供一定的借鉴和参考。
온도민감형원위응효시현재국내외연구신형약물전체계통적일개열점，인구유량호적류동성、교장적체류시간、고효적생물이용도급량호적공제석약성능등우점성위료신형급약계통적주요연구대상。본문이근년래국내외연구온도민감형원위응효적상관문헌，대기기질선택、급약도경급질량공제적연구진행종술，종이위온도민감형원위응효적신형약물연발제공일정적차감화삼고。
Thermo-sensitive gels was a hot spot of research at home and abroad new drug delivery systems now, which had a good liquidity, longer retention time, high bioavailability and good control of drug release performance advantages, so it became a new drug delivery system of the main research object.Based on the research at home and abroad in recent years, its type of matrix selection, routes of administration and quality control of research were summarized, so as to provide certain reference for developing new drugs of thermo-sensitive gels.