CAJ | 학술논문

目的：观察H型高血压患者血压变异性的特点。方法连续选择2011年2月～2013年2月于军事科学院门诊部就诊的80例原发性高血压患者，分别进行血浆同型半胱氨酸（Hcy）水平测定和动态血压监测，根据Hcy水平分为H型高血压组（n=44）和非H型高血压组（n=36），分析比较两组间的血压变异性。结果与非H型高血压患者相比，H型高血压组患者24h平均收缩压标准差（24hSSD）[（15.83±4.02）mmHg vs.（13.25±3.89）mmHg]、白昼收缩压标准差（dSSD）[（16.82±4.98）mmHg vs.（12.75±3.86）mmHg]、白昼舒张压标准差（dDSD）[（10.29±2.23）mmHg vs.（8.62±1.82）mmHg]和夜间收缩压标准差（nSSD）[（12.88±4.54）mmHg vs.（10.12±3.36）mmHg]明显增高，差异具有统计学意义（P均＜0.05）显著。结论与非H型高血压患者相比，H型高血压患者血压变异性增高。
목적：관찰H형고혈압환자혈압변이성적특점。방법련속선택2011년2월～2013년2월우군사과학원문진부취진적80례원발성고혈압환자，분별진행혈장동형반광안산（Hcy）수평측정화동태혈압감측，근거Hcy수평분위H형고혈압조（n=44）화비H형고혈압조（n=36），분석비교량조간적혈압변이성。결과여비H형고혈압환자상비，H형고혈압조환자24h평균수축압표준차（24hSSD）[（15.83±4.02）mmHg vs.（13.25±3.89）mmHg]、백주수축압표준차（dSSD）[（16.82±4.98）mmHg vs.（12.75±3.86）mmHg]、백주서장압표준차（dDSD）[（10.29±2.23）mmHg vs.（8.62±1.82）mmHg]화야간수축압표준차（nSSD）[（12.88±4.54）mmHg vs.（10.12±3.36）mmHg]명현증고，차이구유통계학의의（P균＜0.05）현저。결론여비H형고혈압환자상비，H형고혈압환자혈압변이성증고。
Objective To observe the characteristics of blood pressure variability in patients with H-type hypertension. Methods The patients (n=80) were continuously chosen from the Outpatient Department of Chinese PLA Academy of Military Science from Feb. 2011 to Feb. 2013, and given the detection of plasma homocysteine (Hcy) level and ambulatory blood pressure monitoring. The patients were divided, according to Hcy level, into H-type hypertension group (n=44) and non-H-type hypertension group (n=36). The characteristics of blood pressure variability were compared and analyzed between two groups. Results The levels of 24-h SSD [(15.83± 4.02) mmHg vs. (13.25±3.89) mmHg], dSSD [(16.82±4.98) mmHg vs. (12.75±3.86) mmHg, dDSD [(10.29±2.23) mmHg vs. (8.62±1.82) mmHg], and nSSD [(12.88±4.54) mmHg vs. (10.12±3.36) mmHg] increased significantly in H-type hypertension group compared with non-H-type hypertension group (all P<0.05). Conclusion The blood pressure variability is higher in the patients with H-type hypertension than that in those with non-H-type hypertension.