医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2014年
1期
124-125
,共2页
慢性心功能不全%米力农%血流动力学%疗效
慢性心功能不全%米力農%血流動力學%療效
만성심공능불전%미력농%혈류동역학%료효
chronic Cardiac insufficiency%milrinone%hemodynamics%curative effect
目的：比较米力农与地高辛治疗慢性心功能不全的临床疗效及对血流动力学的影响差异。方法：选择我院2012年2月至2013年9月收治68例慢性心功能不全作为观察对象,按随机数字表分为米力农组34例和地高辛组34例,米力农组在静脉注射米力农,0.375ug-0.75ug/(kg. min),10d为1个疗程,地高辛组口服地高辛,0.125mg/次,qd,10d为1个疗程,治疗前后观察两组患者血流动力学指标中心静脉压、射血分数、心力压力聚积差异,评价两组临床疗效。结果：米力农组与地高辛组治疗后中心静脉压、心力压力聚积均较治疗前明显降低(均P<0.05),射血分数均较治疗前明显升高(均P<0.05),米力农组治疗后中心静脉压、心力压力聚积明显低于对照组(均P<0.05),射血分数明显高于对照组(P<0.05)；米力农组与地高辛组的总有效率分别为94.12%比58.82%,差异具有统计学意义(x2=12.832,P<0.01)。结论：米力农能够有效改善慢性心功能不全的心功能、血流动力学,临床症状有效缓解,临床总有效率明显高于地高辛,且不明显不良反应,值得临床推广使用。
目的：比較米力農與地高辛治療慢性心功能不全的臨床療效及對血流動力學的影響差異。方法：選擇我院2012年2月至2013年9月收治68例慢性心功能不全作為觀察對象,按隨機數字錶分為米力農組34例和地高辛組34例,米力農組在靜脈註射米力農,0.375ug-0.75ug/(kg. min),10d為1箇療程,地高辛組口服地高辛,0.125mg/次,qd,10d為1箇療程,治療前後觀察兩組患者血流動力學指標中心靜脈壓、射血分數、心力壓力聚積差異,評價兩組臨床療效。結果：米力農組與地高辛組治療後中心靜脈壓、心力壓力聚積均較治療前明顯降低(均P<0.05),射血分數均較治療前明顯升高(均P<0.05),米力農組治療後中心靜脈壓、心力壓力聚積明顯低于對照組(均P<0.05),射血分數明顯高于對照組(P<0.05)；米力農組與地高辛組的總有效率分彆為94.12%比58.82%,差異具有統計學意義(x2=12.832,P<0.01)。結論：米力農能夠有效改善慢性心功能不全的心功能、血流動力學,臨床癥狀有效緩解,臨床總有效率明顯高于地高辛,且不明顯不良反應,值得臨床推廣使用。
목적：비교미력농여지고신치료만성심공능불전적림상료효급대혈류동역학적영향차이。방법：선택아원2012년2월지2013년9월수치68례만성심공능불전작위관찰대상,안수궤수자표분위미력농조34례화지고신조34례,미력농조재정맥주사미력농,0.375ug-0.75ug/(kg. min),10d위1개료정,지고신조구복지고신,0.125mg/차,qd,10d위1개료정,치료전후관찰량조환자혈류동역학지표중심정맥압、사혈분수、심력압력취적차이,평개량조림상료효。결과：미력농조여지고신조치료후중심정맥압、심력압력취적균교치료전명현강저(균P<0.05),사혈분수균교치료전명현승고(균P<0.05),미력농조치료후중심정맥압、심력압력취적명현저우대조조(균P<0.05),사혈분수명현고우대조조(P<0.05)；미력농조여지고신조적총유효솔분별위94.12%비58.82%,차이구유통계학의의(x2=12.832,P<0.01)。결론：미력농능구유효개선만성심공능불전적심공능、혈류동역학,림상증상유효완해,림상총유효솔명현고우지고신,차불명현불량반응,치득림상추엄사용。
Objective:To compare the clinical effect of milrinone and digoxin in the treatment of chronic and its infl Cardiac insufficiency uence on hemodynamics. Methods:in our hospital from 2012 February to 2013 September, 68 cases of chronic were sele Cardiac insufficiency cted, randomly divided into milrinone group 34 cases and digoxin group 34 cases, milrinone group in the intravenous injection of milrinone, 0. 375ug-0. 75ug/ (kg. min), 10d for 1 courses, to the digoxin group oral digoxin, 0. 125mg/ QD, 10D, for 1 courses of treatment, two groups were observed before and after hemodynamic indexes of central venous pressure, ejection fraction, cardiac pressure accumulation difference, two groups of clinical curative effect evaluation. Results:the milrinone group and the digoxin group after the treatment of central venous pressure, cardiac contractility pres-sure accumulation were significantly lower than that before treatment (P< 0. 05), ejection fraction than before treatment significantly increased (P<0. 05), milrinone group after treatment of central venous pressure, cardiac contractility pressure accumulation was significantly lower than that of the control group (all P<0. 05), ejection fraction was significantly higher than the control group (P<0. 05);milrinone group and the digox-in group the total effective rate was 94. 12% compared with 58. 82%, the difference was statistically significant (x2 =12. 832, P<0. 01). Conclu-sion:milrinone can improve the cardiac function, hemodynamics in chronic , effectively Cardiac insufficiency alleviate the clinical symptoms, the clinical total effective rate was significantly higher than that of digoxin, and no obvious adverse reactions, it is worthy of clinical use.
