医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2014年
1期
18-20
,共3页
非酒精性脂肪肝病%肝爽颗粒%阿托伐他汀钙片%疗效观察
非酒精性脂肪肝病%肝爽顆粒%阿託伐他汀鈣片%療效觀察
비주정성지방간병%간상과립%아탁벌타정개편%료효관찰
Nonalcoholic fatty liver disease%Ganshuang Keli%Atorvastatin Calcium Tablets%Clinical observation
目的：通过观察肝爽颗粒治疗非酒精性脂肪肝病的临床疗效对其有效性进行评价,从而为其中医治疗非酒精性脂肪肝病提供一定的依据。方法：根据随机、对照原则,将符合观察标准60例患者随机分为两组进行治疗。治疗组予以口服肝爽颗粒,每次3g,一天3次,加阿托伐他汀钙片,10mg/次,一天1次,三个月为一个疗程。对照组为纯西药治疗,即口服阿托伐他汀钙片,10mg/次,一天1次,三个月为一个疗程。治疗过程中,观察患者主要症状、肝功能、血脂、肝脏彩超变化。结果：治疗组症状明显改善,与对照组比较差异有统计学意义(P<0.05)。治疗组临床疗效总有效率达86.67%,对照组总有效率达66.67%,两组比较差异有明显统计学意义(P<0.01)；治疗组TC、TG、HDL-C、LDL-C与对照组比差异无统计学意义(P >0.05)。治疗组ALT、AST、GGT、肝脏彩超改善情况较对照组差异有统计学意义(P<0.01)。结论：肝爽颗粒治疗非酒精性脂肪肝病具有较好疗效,不良反应少,值得临床推广应用。
目的：通過觀察肝爽顆粒治療非酒精性脂肪肝病的臨床療效對其有效性進行評價,從而為其中醫治療非酒精性脂肪肝病提供一定的依據。方法：根據隨機、對照原則,將符閤觀察標準60例患者隨機分為兩組進行治療。治療組予以口服肝爽顆粒,每次3g,一天3次,加阿託伐他汀鈣片,10mg/次,一天1次,三箇月為一箇療程。對照組為純西藥治療,即口服阿託伐他汀鈣片,10mg/次,一天1次,三箇月為一箇療程。治療過程中,觀察患者主要癥狀、肝功能、血脂、肝髒綵超變化。結果：治療組癥狀明顯改善,與對照組比較差異有統計學意義(P<0.05)。治療組臨床療效總有效率達86.67%,對照組總有效率達66.67%,兩組比較差異有明顯統計學意義(P<0.01)；治療組TC、TG、HDL-C、LDL-C與對照組比差異無統計學意義(P >0.05)。治療組ALT、AST、GGT、肝髒綵超改善情況較對照組差異有統計學意義(P<0.01)。結論：肝爽顆粒治療非酒精性脂肪肝病具有較好療效,不良反應少,值得臨床推廣應用。
목적：통과관찰간상과립치료비주정성지방간병적림상료효대기유효성진행평개,종이위기중의치료비주정성지방간병제공일정적의거。방법：근거수궤、대조원칙,장부합관찰표준60례환자수궤분위량조진행치료。치료조여이구복간상과립,매차3g,일천3차,가아탁벌타정개편,10mg/차,일천1차,삼개월위일개료정。대조조위순서약치료,즉구복아탁벌타정개편,10mg/차,일천1차,삼개월위일개료정。치료과정중,관찰환자주요증상、간공능、혈지、간장채초변화。결과：치료조증상명현개선,여대조조비교차이유통계학의의(P<0.05)。치료조림상료효총유효솔체86.67%,대조조총유효솔체66.67%,량조비교차이유명현통계학의의(P<0.01)；치료조TC、TG、HDL-C、LDL-C여대조조비차이무통계학의의(P >0.05)。치료조ALT、AST、GGT、간장채초개선정황교대조조차이유통계학의의(P<0.01)。결론：간상과립치료비주정성지방간병구유교호료효,불량반응소,치득림상추엄응용。
Objective:By observing the Clinical curative effect of usinng Ganshuang Keli to treat the non-alcoholic fatty liver disease and e-valuate its effectiveness,which was provided a certain basis on treating the non-alcoholic fatty liver disease using traditional Chinese medicine . Method:According to the principle of randomized, controlled,to observe the standard of 60 patients were randomly divided into two groups . The treat-ment group given oral Ganshuang Keli, 3 g per time, 3 times a day and Atorvastatin Calcium Tablets ,10 mg per time, once a day. The control group by oral Atorvastatin Calcium Tablets,10 mg per time, once a day. Two groups of all three months for a period of treatment. In the process of the treat-ment,observing the patients' clinical symptoms、the function of liver、lipid levels、color doppler ultrasound images. Result:To compare with control group ,the symptoms of treatment group have markedly improved after three months'treatment,the difference was statistically significant(P<0.05). The total effective rate of treatment group is 86. 67%,and the control group is 66. 67%. The differences between the two groups have obvious statisti-cal significance(P<0. 01). The differences in TC、TG 、HDL-C and LDL-C between the two groups have no statistical significance . The differ-ences in ALT、AST、GGT、Color doppler ultrasound images between two groups have obvious statistical significance. Conclusion:Usinng Ganshuang Ke-li to treat he non-alcoholic fatty liver disease has a good curative effect, less adverse reactions, worthy of clinical popularization and application and Atorvastatin Calcium Tablets treatment.
