CAJ | 학술논문

目的：研究Ⅲ型肺结核病合并Ⅳ型肺结核患者应用巩固化疗的临床疗效。方法选取2009年1月-2012年6月肇庆市结核病防治所收治的200例Ⅲ型肺结核合并Ⅳ型肺结核患者，首先选用异烟肼、利福平、乙胺丁醇、异烟肼及吡嗪酰胺药物进行强化期治疗2个月，而后将这些患者平均分成两组，观察组（A组）每周1次利福喷丁，外加每周2次异烟肼；对照组（B组）每天应用1次利福平、异烟肼，以6个月为1个疗程。结果在治疗结束后，两组患者在痰培养、结核病灶及胸水吸收等比较差异无统计学意义。在肝功能损害上，观察组低于对照组。结论对Ⅲ型肺结核合并Ⅳ型肺结核患者实施每周1次的巩固治疗，能够取得显著疗效，提高患者的耐受性，减轻毒副作用。
목적：연구Ⅲ형폐결핵병합병Ⅳ형폐결핵환자응용공고화료적림상료효。방법선취2009년1월-2012년6월조경시결핵병방치소수치적200례Ⅲ형폐결핵합병Ⅳ형폐결핵환자，수선선용이연정、리복평、을알정순、이연정급필진선알약물진행강화기치료2개월，이후장저사환자평균분성량조，관찰조（A조）매주1차리복분정，외가매주2차이연정；대조조（B조）매천응용1차리복평、이연정，이6개월위1개료정。결과재치료결속후，량조환자재담배양、결핵병조급흉수흡수등비교차이무통계학의의。재간공능손해상，관찰조저우대조조。결론대Ⅲ형폐결핵합병Ⅳ형폐결핵환자실시매주1차적공고치료，능구취득현저료효，제고환자적내수성，감경독부작용。
Objective To study TB pleurisy patients merger consolidation chemotherapy clinical efficacy. Methods In the hospital from January 2009 to June 2012 were treated 200 cases of TB pleurisy patients combined, the first choice of rifampicin, ethambutol, isoniazid and pyrazinamide in the intensive phase of treatment of two drugs months, and after these patients were divided into two groups, the observation group (A group) once weekly rifapentine plus isoniazid twice a week; the control group (B) applied once daily rifampin, isoniazid hydrazine to six months for a course of treatment. Results After treatment, the two groups of patients in the sputum, pleural fluid absorption tuberculosis and no difference was not statistical y significant. In liver dysfunction, the observation group than the control group. Conclusion Patients with TB pleurisy implemented merger consolidation therapy once a week, it is possible to obtain a significant effect, improve the patient's tolerance, reduce side effects.