医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2013年
36期
69-70
,共2页
冠心病%瘦素%肌钙蛋白I%C型钠尿肽%稳定性心绞痛%不稳定心绞痛%急性心肌梗死
冠心病%瘦素%肌鈣蛋白I%C型鈉尿肽%穩定性心絞痛%不穩定心絞痛%急性心肌梗死
관심병%수소%기개단백I%C형납뇨태%은정성심교통%불은정심교통%급성심기경사
coronary heart diseases (CHD)%leptin tropouin I (cTnI)%c-tyre natriuretic peptide (CNP)%stable angina pectoris(SAP)%unstable angina pectoris(UAP)%acute myocardial in faretim(AMI)
目的：探讨了冠心病患者血浆Leptin和血清cTnI CNP水平的变化及临床意义。方法应用放射免疫分析法和生化法对90例冠心病患者进行了血浆Leptin和血清cTnI、CNP水平检测，其中稳定性心绞痛（SAP）41例，不稳定心绞痛（UAP）34例，急性心肌梗死（AMI）15例，并与35名正常健康人作比较。结果冠心病患者血浆Leptin和血清cTnI、CNP水平均非常显著地高于正常人组（P＜0.01），AMI和UAP组水平又明显高于SAP组（P＜0.01），血浆Leptin水平与cTnI、CNP水平呈显著正相关（r=0.61380.5926 P＜0.01）。结论检测冠心病患者血浆Leptin和血清cTnI、CNP水平的变化与CHD的发生和发展与疾病的预后观察均具有重要的临床价值。
目的：探討瞭冠心病患者血漿Leptin和血清cTnI CNP水平的變化及臨床意義。方法應用放射免疫分析法和生化法對90例冠心病患者進行瞭血漿Leptin和血清cTnI、CNP水平檢測，其中穩定性心絞痛（SAP）41例，不穩定心絞痛（UAP）34例，急性心肌梗死（AMI）15例，併與35名正常健康人作比較。結果冠心病患者血漿Leptin和血清cTnI、CNP水平均非常顯著地高于正常人組（P＜0.01），AMI和UAP組水平又明顯高于SAP組（P＜0.01），血漿Leptin水平與cTnI、CNP水平呈顯著正相關（r=0.61380.5926 P＜0.01）。結論檢測冠心病患者血漿Leptin和血清cTnI、CNP水平的變化與CHD的髮生和髮展與疾病的預後觀察均具有重要的臨床價值。
목적：탐토료관심병환자혈장Leptin화혈청cTnI CNP수평적변화급림상의의。방법응용방사면역분석법화생화법대90례관심병환자진행료혈장Leptin화혈청cTnI、CNP수평검측，기중은정성심교통（SAP）41례，불은정심교통（UAP）34례，급성심기경사（AMI）15례，병여35명정상건강인작비교。결과관심병환자혈장Leptin화혈청cTnI、CNP수평균비상현저지고우정상인조（P＜0.01），AMI화UAP조수평우명현고우SAP조（P＜0.01），혈장Leptin수평여cTnI、CNP수평정현저정상관（r=0.61380.5926 P＜0.01）。결론검측관심병환자혈장Leptin화혈청cTnI、CNP수평적변화여CHD적발생화발전여질병적예후관찰균구유중요적림상개치。
Objective : To explore the clinical significance of changes of plasma leptin and serum cTnI CNP levels in patients with coronary heart diseases(CHD) Methods: plasma leptin and serum CNP(with Ria) serum cTnI (with Biochemistry) levels were determined in 90 patients with CHD(41 SAP ,34 UAP, 15 AMI)and 35 controls . Results :plasma leptin and serum cTnI CNP levels in patients with CHD were significance higher than those in contrals(P<0.01)Among the patients with CHD the magnitude of changes of the levels of plasma leptin and serum cTnI CNP levels in AMI UAP groups were significantly higher than those in SAP groups(P<0.05)plasma leptin levels were positively correlated with serum cTnI CNP levels (r=0.6138 0.5926 P<0.01)conclusions : plasma leptin and serum cTnI CNP levels were closely related to the diseases process of CHD and were of great clinical importance for assessment of the diseases and outcome prediction.
