安徽医科大学学报
安徽醫科大學學報
안휘의과대학학보
ACTA UNIVERSITY MEDICINALIS ANHUI
2014年
6期
785-788
,共4页
马玉婷%董毅%汪凯%赵菁%王龙%刘勇%张玉%李慧%耿峰%陈学全
馬玉婷%董毅%汪凱%趙菁%王龍%劉勇%張玉%李慧%耿峰%陳學全
마옥정%동의%왕개%조정%왕룡%류용%장옥%리혜%경봉%진학전
快感缺失%童年创伤%精神分裂症
快感缺失%童年創傷%精神分裂癥
쾌감결실%동년창상%정신분렬증
anhedonia%childhood trauma%schizophrenia
目的：探讨精神分裂症患者快感缺失与童年创伤经历的关系。方法采用中文版修订社会快感缺失量表(RSAS-C)、中文版修订躯体快感缺失量表(RPAS-C)和童年创伤问卷( CTQ)对198例精神分裂症患者和271例正常健康者进行评估,分析快感缺失与童年创伤间的关系。结果患者组RSAS-C评分(13．32±6．12)、RPAS-C评分(19．04±8．53)、CTQ总分(47．63±13．49)及其各因子分均显著高于正常组(分别为10．40±5．05,16．80±7．89,38．82±10．05),差异有统计学意义( P<0．05)；患者组RSAS-C评分、RPAS-C评分与阳性与阴性症状量表( PANSS)总分及阴性症状分均呈正相关(rs =0．266~0．439,P<0．01)；患者组RSAS-C评分(rs =0．419,P<0．01)和RPAS-C评分(rs =0．322,P<0．01)与CTQ总分呈正相关,控制PANSS总分后,快感缺失评分与童年创伤评分间的相关性仍存在。结论精神分裂症患者快感缺失程度较高,与童年创伤经历之间存在关联,提示早年的创伤经历可能会影响个体对躯体及社会交往快乐的体验能力。
目的：探討精神分裂癥患者快感缺失與童年創傷經歷的關繫。方法採用中文版脩訂社會快感缺失量錶(RSAS-C)、中文版脩訂軀體快感缺失量錶(RPAS-C)和童年創傷問捲( CTQ)對198例精神分裂癥患者和271例正常健康者進行評估,分析快感缺失與童年創傷間的關繫。結果患者組RSAS-C評分(13．32±6．12)、RPAS-C評分(19．04±8．53)、CTQ總分(47．63±13．49)及其各因子分均顯著高于正常組(分彆為10．40±5．05,16．80±7．89,38．82±10．05),差異有統計學意義( P<0．05)；患者組RSAS-C評分、RPAS-C評分與暘性與陰性癥狀量錶( PANSS)總分及陰性癥狀分均呈正相關(rs =0．266~0．439,P<0．01)；患者組RSAS-C評分(rs =0．419,P<0．01)和RPAS-C評分(rs =0．322,P<0．01)與CTQ總分呈正相關,控製PANSS總分後,快感缺失評分與童年創傷評分間的相關性仍存在。結論精神分裂癥患者快感缺失程度較高,與童年創傷經歷之間存在關聯,提示早年的創傷經歷可能會影響箇體對軀體及社會交往快樂的體驗能力。
목적：탐토정신분렬증환자쾌감결실여동년창상경력적관계。방법채용중문판수정사회쾌감결실량표(RSAS-C)、중문판수정구체쾌감결실량표(RPAS-C)화동년창상문권( CTQ)대198례정신분렬증환자화271례정상건강자진행평고,분석쾌감결실여동년창상간적관계。결과환자조RSAS-C평분(13．32±6．12)、RPAS-C평분(19．04±8．53)、CTQ총분(47．63±13．49)급기각인자분균현저고우정상조(분별위10．40±5．05,16．80±7．89,38．82±10．05),차이유통계학의의( P<0．05)；환자조RSAS-C평분、RPAS-C평분여양성여음성증상량표( PANSS)총분급음성증상분균정정상관(rs =0．266~0．439,P<0．01)；환자조RSAS-C평분(rs =0．419,P<0．01)화RPAS-C평분(rs =0．322,P<0．01)여CTQ총분정정상관,공제PANSS총분후,쾌감결실평분여동년창상평분간적상관성잉존재。결론정신분렬증환자쾌감결실정도교고,여동년창상경력지간존재관련,제시조년적창상경력가능회영향개체대구체급사회교왕쾌악적체험능력。
Objective To explore the relationship between anhedonia and childhood trauma in patients with schizo-phrenia. Methods 198 schizophrenic patients and 271 healthy subjects were asked to completed the Revised So-cial Anhedonia Scale-Chinese Version ( RSAS-C) , the Revised Physical Anhedonia Scale-Chinese Version ( RPAS-C) and the Childhood Trauma Questionnaire (CTQ). Results In the patients group, the RSAS-C score(13. 32 ± 6. 12), RPAS-C score(19. 04 ± 8. 53), CTQ total score(47. 63 ± 13. 49) and its five factors scores were signifi-cantly higher than those in the control group ( 10. 40 ± 5. 05 , 16. 80 ± 7. 89 , 38. 82 ± 10. 05 , respectively ) ( P<0. 05). Correlation analysis showed that in the patients group, the RSAS-C score and RPAS-C score were signifi-cantly positively correlated with the Positive and Negative Syndrome Scale ( PANSS ) total score and its negative score(rs=0. 266~0. 439,P<0. 01). The RSAS-C score(rs=0. 419,P<0. 01) and RPAS-C score(rs=0. 322,P<0. 01) were also significantly positively correlated with CTQ total score in the patients group. After controlling PANSS total score, there were also correlations between RSAS-C, RPAS-C scores and CTQ scores. Conclusion Anhedonia is related to childhood trauma in schizophrenia patients, suggesting that the trauma during childhood may affect the ability to experience physical and interpersonal pleasure.
