临床超声医学杂志
臨床超聲醫學雜誌
림상초성의학잡지
JOURNAL OF ULTRASOUND IN CLINICAL M，EDICINE
2014年
2期
52-54
,共3页
超声检查%造影剂%高强度聚焦超声%肝动脉栓塞化疗术%原发性肝癌
超聲檢查%造影劑%高彊度聚焦超聲%肝動脈栓塞化療術%原髮性肝癌
초성검사%조영제%고강도취초초성%간동맥전새화료술%원발성간암
Ultrasonography%Contrast agent%High-intensity focused ultrasound%Transcatheter arterial chemoembolization%Hepatocelular carcinoma
目的：探讨超声造影对动脉栓塞化疗（TACE）与高强度聚焦超声（HIFU）联合治疗原发性肝癌的临床疗效评价。方法经TACE与HIFU联合治疗原发性肝癌（联合组）患者22例，经单纯TACE组54例，单纯HIFU治疗组41例。经TACE与HIFU联合治疗前及治疗后1周进行超声造影检查，观察肿瘤组织内部有无残留血供和遗漏病灶，并对经TACE治疗1～3次未完全灭活的病灶行HIFU补充治疗。结果 TACE组和HIFU组肿瘤灭活率均低于联合组，肿瘤残存率均高于联合组（P＜0．05）；联合组6个月、1年、2年生存率分别为100％、90．9％、81．8％，高于TACE组和HIFU组（P＜0．05）。结论超声造影对TACE与HIFU联合治疗原发性肝癌的临床疗效能够做出准确判断，显示经TACE与HIFU联合治疗肝癌的疗效明显优于单纯TACE或HIFU治疗。
目的：探討超聲造影對動脈栓塞化療（TACE）與高彊度聚焦超聲（HIFU）聯閤治療原髮性肝癌的臨床療效評價。方法經TACE與HIFU聯閤治療原髮性肝癌（聯閤組）患者22例，經單純TACE組54例，單純HIFU治療組41例。經TACE與HIFU聯閤治療前及治療後1週進行超聲造影檢查，觀察腫瘤組織內部有無殘留血供和遺漏病竈，併對經TACE治療1～3次未完全滅活的病竈行HIFU補充治療。結果 TACE組和HIFU組腫瘤滅活率均低于聯閤組，腫瘤殘存率均高于聯閤組（P＜0．05）；聯閤組6箇月、1年、2年生存率分彆為100％、90．9％、81．8％，高于TACE組和HIFU組（P＜0．05）。結論超聲造影對TACE與HIFU聯閤治療原髮性肝癌的臨床療效能夠做齣準確判斷，顯示經TACE與HIFU聯閤治療肝癌的療效明顯優于單純TACE或HIFU治療。
목적：탐토초성조영대동맥전새화료（TACE）여고강도취초초성（HIFU）연합치료원발성간암적림상료효평개。방법경TACE여HIFU연합치료원발성간암（연합조）환자22례，경단순TACE조54례，단순HIFU치료조41례。경TACE여HIFU연합치료전급치료후1주진행초성조영검사，관찰종류조직내부유무잔류혈공화유루병조，병대경TACE치료1～3차미완전멸활적병조행HIFU보충치료。결과 TACE조화HIFU조종류멸활솔균저우연합조，종류잔존솔균고우연합조（P＜0．05）；연합조6개월、1년、2년생존솔분별위100％、90．9％、81．8％，고우TACE조화HIFU조（P＜0．05）。결론초성조영대TACE여HIFU연합치료원발성간암적림상료효능구주출준학판단，현시경TACE여HIFU연합치료간암적료효명현우우단순TACE혹HIFU치료。
Objective To explore the value of contrast-enhanced ultrasonography in evaluating curative effect of TACE combined with HIFU for treating primary hepatocellular carcinoma(HCC). Methods Fifty-four patients with HCC in TACE group, 41 patients in HIFU group and 22 patients in combined group were enrolled. All patients were examined using contrast-enhanced ultrasonography before and one week after therapy. Residual blood supply and missed lesions inside tumor tissues were observed. The lesion of incomplete deactivation were treated by HIFU in time. Results Contrast-enhanced ultrasonography showed that tumor inactivated rates were lower in TACE group and HIFU group than that in combined group, and tumor residual rates were significantly higher in TACE group and HIFU group than that in combined group (P<0.05). In combined group, six months, one-year and two-year survival rates were 100%,90.9%and 81.8%, respectively. They were higher than those in TACE or HIFU group ( P<0 . 05 ) . Conclusion Contrast-enhanced ultrasonography can accurately evaluate curative effect of treating HCC . Curative effect of TACE combined with HIFU for treating HCC is much better than TACE or HIFU treatment.
