中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
CHINESE JOURNAL OF INFORMATION ON TRADITIONAL CHINESE MEDICINE
2014年
2期
85-87
,共3页
李钦青%郭蕾%张俊龙%柴金苗
李欽青%郭蕾%張俊龍%柴金苗
리흠청%곽뢰%장준룡%시금묘
复方天麻钩藤口腔崩解片%质量标准%天麻素%高效液相色谱法
複方天痳鉤籐口腔崩解片%質量標準%天痳素%高效液相色譜法
복방천마구등구강붕해편%질량표준%천마소%고효액상색보법
Fufang Tianma Gouteng Orally Disintegrating Tablets%quality standard%gastrodin%HPLC
目的：建立复方天麻钩藤口腔崩解片的质量标准。方法采用薄层色谱法对制剂中的天麻、钩藤、当归、白芍进行定性鉴别,采用高效液相色谱法测定制剂中的天麻素。结果薄层鉴别图谱清晰,阴性对照无干扰。天麻素进样量在0.1912～1.1472μg 范围内线性关系良好(r＝0.9999),平均回收率为97.72%(RSD＝1.40%,n＝6)。结论本方法简便、重复性好,可有效控制制剂的质量。
目的：建立複方天痳鉤籐口腔崩解片的質量標準。方法採用薄層色譜法對製劑中的天痳、鉤籐、噹歸、白芍進行定性鑒彆,採用高效液相色譜法測定製劑中的天痳素。結果薄層鑒彆圖譜清晰,陰性對照無榦擾。天痳素進樣量在0.1912～1.1472μg 範圍內線性關繫良好(r＝0.9999),平均迴收率為97.72%(RSD＝1.40%,n＝6)。結論本方法簡便、重複性好,可有效控製製劑的質量。
목적：건립복방천마구등구강붕해편적질량표준。방법채용박층색보법대제제중적천마、구등、당귀、백작진행정성감별,채용고효액상색보법측정제제중적천마소。결과박층감별도보청석,음성대조무간우。천마소진양량재0.1912～1.1472μg 범위내선성관계량호(r＝0.9999),평균회수솔위97.72%(RSD＝1.40%,n＝6)。결론본방법간편、중복성호,가유효공제제제적질량。
Objective To establish the quality standard of Fufang Tianma Gouteng Orally Disintegrating Tablets. Methods Gastrodiae Rhizoma, Uncariae Ramulus Cum Uncis, Angelicae Sinensis Radix and Paeoniae Radix Alba in the preparation were identified by TLC, the content of gastrodin in gastrodia was determined by HPLC. Results The herbs of preparation could be identified by TLC without interference. Gastrodin showed a good linear relationship in the range of 0.191 2-1.147 2 μg (r=0.999 9). The average recovery was 97.72% (RSD=1.40%, n=6). Conclusion The methods are available with a good reproducibility, and can control the quality of the preparation effectively.
