中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
13期
113-114
,共2页
结节性痒疹%他扎罗汀凝胶%NB-UVB%自拟除湿散结汤
結節性癢疹%他扎囉汀凝膠%NB-UVB%自擬除濕散結湯
결절성양진%타찰라정응효%NB-UVB%자의제습산결탕
Generalized nodular prurigo%Tazarotene gel%NB-UVB%Chushi Sanjie decoction
目的：观察口服自拟除湿散结汤联合他扎罗汀凝胶外用及窄谱中波紫外线照射治疗泛发性结节性痒疹的疗效。方法：将入选的112例泛发性结节性痒疹患者采用随机方式分为治疗组（A组，n＝38），给予外用0.1%他扎罗汀凝胶，每晚1次，并用窄谱中波紫外线（NB-UVB）照射，隔日1次；对照1组（B组，n＝36），单纯给予他扎罗汀凝胶外用；对照2组（C组，n＝38），单纯给予NB-UVB照射；3组患者均口服自拟除湿散结汤。4、8周后分别评价疗效，疗程结束12周随访复发情况。结果：治疗1个疗程后，3组有效率分别为68.4%、44.4%、47.4%，3组间比较差异有显著意义（P<0.05），A组疗效优于B组和C组；治疗2个疗程后，3组有效率分别为89.5%、61.1%、63.2%，3组间比较差异有显著意义（P<0.01），A组疗效明显优于B组和C组。A组复发率也明显低于B组和C组。结论：口服自拟除湿散结汤联合他扎罗汀凝胶外用及窄谱中波紫外线照射治疗结节性痒疹疗效显著。
目的：觀察口服自擬除濕散結湯聯閤他扎囉汀凝膠外用及窄譜中波紫外線照射治療汎髮性結節性癢疹的療效。方法：將入選的112例汎髮性結節性癢疹患者採用隨機方式分為治療組（A組，n＝38），給予外用0.1%他扎囉汀凝膠，每晚1次，併用窄譜中波紫外線（NB-UVB）照射，隔日1次；對照1組（B組，n＝36），單純給予他扎囉汀凝膠外用；對照2組（C組，n＝38），單純給予NB-UVB照射；3組患者均口服自擬除濕散結湯。4、8週後分彆評價療效，療程結束12週隨訪複髮情況。結果：治療1箇療程後，3組有效率分彆為68.4%、44.4%、47.4%，3組間比較差異有顯著意義（P<0.05），A組療效優于B組和C組；治療2箇療程後，3組有效率分彆為89.5%、61.1%、63.2%，3組間比較差異有顯著意義（P<0.01），A組療效明顯優于B組和C組。A組複髮率也明顯低于B組和C組。結論：口服自擬除濕散結湯聯閤他扎囉汀凝膠外用及窄譜中波紫外線照射治療結節性癢疹療效顯著。
목적：관찰구복자의제습산결탕연합타찰라정응효외용급착보중파자외선조사치료범발성결절성양진적료효。방법：장입선적112례범발성결절성양진환자채용수궤방식분위치료조（A조，n＝38），급여외용0.1%타찰라정응효，매만1차，병용착보중파자외선（NB-UVB）조사，격일1차；대조1조（B조，n＝36），단순급여타찰라정응효외용；대조2조（C조，n＝38），단순급여NB-UVB조사；3조환자균구복자의제습산결탕。4、8주후분별평개료효，료정결속12주수방복발정황。결과：치료1개료정후，3조유효솔분별위68.4%、44.4%、47.4%，3조간비교차이유현저의의（P<0.05），A조료효우우B조화C조；치료2개료정후，3조유효솔분별위89.5%、61.1%、63.2%，3조간비교차이유현저의의（P<0.01），A조료효명현우우B조화C조。A조복발솔야명현저우B조화C조。결론：구복자의제습산결탕연합타찰라정응효외용급착보중파자외선조사치료결절성양진료효현저。
Objective: To observe clinical effects of Chushi Sanjie decoction plus tazarotene gel and narrow-band UV on treating generalized nodular prurigo. Methods: 112 patients were randomly divided into two groups, the treatment group of 38 cases named A was given 0.1% tazarotene gel for every night and irradiated with a narrow-band UVB (NB-UVB) for every other day; the control group 1 named B was given tazarotene gel solo; the control group 2 named C was given NB-UVB; all groups were treated with Chushi Sanjie decoction, evaluating the effects in 4 and 8 weeks. Results: The total efficacy in three groups were 68.4%, 44.4%, 47.4% after one treatment with a significant difference (P<0.05), clinical effects in A group were better; the rate was 89.5%, 61.1%, 63.2% after two treatment with a high significant difference (P<0.05), clinical effects in group A were better with a low recurrence. Conclusion: Chushi Sanjie decoction plus tazarotene gel and narrow-band UV has good clinical effects on treating generalized nodular prurigo.
