CAJ | 학술논문

目的：通过观察口服二甲双胍缓释片，合并中药桃仁承气汤加味治疗2型糖尿病胰岛素抵抗证属痰瘀互结证的临床效果，探讨中药的作用机制。方法：80例患者随机分为治疗组和对照组，40例治疗组给予桃仁承气汤加味合并口服二甲双胍缓释片1.0g，2次/日，40例对照组口服二甲双胍缓释片1.0g，2次/d，三个月后观察临床症状，胰岛素抵抗改善情况，判定疗效。结果：治疗组40例，显效15例（37.5%），有效20例（50.0%），无效5例（12.5%），总有效率87.5%。对照组40例，显效11例（27.5%），有效18例（45.0%），无效11例（27.5%），总有效率72.5%。结论：中西医结合论证2型糖尿病证属痰瘀互结证的胰岛素抵抗，疗效显著。
목적：통과관찰구복이갑쌍고완석편，합병중약도인승기탕가미치료2형당뇨병이도소저항증속담어호결증적림상효과，탐토중약적작용궤제。방법：80례환자수궤분위치료조화대조조，40례치료조급여도인승기탕가미합병구복이갑쌍고완석편1.0g，2차/일，40례대조조구복이갑쌍고완석편1.0g，2차/d，삼개월후관찰림상증상，이도소저항개선정황，판정료효。결과：치료조40례，현효15례（37.5%），유효20례（50.0%），무효5례（12.5%），총유효솔87.5%。대조조40례，현효11례（27.5%），유효18례（45.0%），무효11례（27.5%），총유효솔72.5%。결론：중서의결합론증2형당뇨병증속담어호결증적이도소저항，료효현저。
Objective: To investigate the oral metformin tablets combined with Taoren Chengqi decoction for insulin resistance in diabetes 2, discuss the mechanism of TCM. Methods: 80 patients were randomly divided into treatment group and control group, 40 cases in the treatment group were given Taoren Chengqi decoction combined with oral metformin tablets 1.0g, 2 times a day, 40 cases in the control group were treated with metformin tablets 1.0g, 2 times a day. Three months later, clinical symptoms and insulin resistance to determine efficacy were observed to determine efficacy. Results: In the treatment group, 40 cases were cured, 15 cases (37.5%) markedly effective, 20 cases (50.0%) effective, 5 cases (12.5%) invalid, the total efficacy was 87.5%. In the control group, 40 cases markedly effective in 11 cases (27.5%), effective in 18 cases (45.0%), invalid in 11 cases (27.5%), the total efficiency was 72.5%. Conclusion: The integrative medicine for insulin resistance of Tanyu Hujie type has good clinical efficacy.