CAJ | 학술논문

目的：探讨帕罗西汀联合心理干预对伴发抑郁症的功能性消化不良患者的临床疗效。方法：选取近三年我院消化专科收治的功能性消化不良伴抑郁症患者68例，按照数字表格法随机分为两组，每组34例。对照组采用抗消化不良药物治疗，观察组在对照组的基础上给予帕罗西汀联合心理干预，观察两组患者的临床疗效。结果：观察组患者的总有效率为94．12％明显高于对照组的73．53％（ X2＝3．904，P＝0．048）；治疗后两组患者的GSRS评分、SDS评分及HRSD评分均较治疗前明显改善（ P＜0．05），观察组患者较对照组改善更显著（ P＜0．05）。结论：帕罗西汀联合心理干预治疗功能性消化不良伴抑郁症可显著提高疗效，明显改善患者的抑郁情绪，提高患者的生活质量。
목적：탐토파라서정연합심리간예대반발억욱증적공능성소화불량환자적림상료효。방법：선취근삼년아원소화전과수치적공능성소화불량반억욱증환자68례，안조수자표격법수궤분위량조，매조34례。대조조채용항소화불량약물치료，관찰조재대조조적기출상급여파라서정연합심리간예，관찰량조환자적림상료효。결과：관찰조환자적총유효솔위94．12％명현고우대조조적73．53％（ X2＝3．904，P＝0．048）；치료후량조환자적GSRS평분、SDS평분급HRSD평분균교치료전명현개선（ P＜0．05），관찰조환자교대조조개선경현저（ P＜0．05）。결론：파라서정연합심리간예치료공능성소화불량반억욱증가현저제고료효，명현개선환자적억욱정서，제고환자적생활질량。
Objective:To investigate the clinical efficacy of paroxetine combined with psychotherapy for functional dyspepsia associated with depression .Method: 68 cases of functional dyspepsia associated with depression in specialist dyspepsia of our hospital according to the digital form were randomly divided into two groups , and 34 cases were in each group .The control group was given anti-indigestion medication , while the observation group was given paroxetine and psychotherapy on the basis of the control group , and the clinical efficacy was observed between the two groups .Result: The total effective rate of the observation group was 94.12%, which was significantly higher than 73.53%of the control group (X2=3.904, P=0.048); After the treatment , the GSRS score , SDS score and HRSD scores of the two groups had improved compared with before (P<0.05), and the observation group improved more significantly (P<0.05).Conclusion: Paroxe-tine combined with psychotherapy in treating functional dyspepsia with depression can significantly improve the efficacy, and it can significant improve the patients with depression , and improve the patient's quality of life.