CAJ | 학술논문

目的：建立农吉利碱凝胶剂质量标准，并进行初步稳定性考察。方法：通过含量测定、体外透皮试验、初步稳定性考察对农吉利碱凝胶剂进行综合评价。结果：农吉利碱在1.6μg/mL~102.4μg/mL的浓度范围内线性关系良好，平均回收率为100.75%，RSD为0.82%（n=6）。结论：建立的质量评价方法专属性良好，准确可靠，能有效控制农吉利碱凝胶剂的质量。
목적：건립농길리감응효제질량표준，병진행초보은정성고찰。방법：통과함량측정、체외투피시험、초보은정성고찰대농길리감응효제진행종합평개。결과：농길리감재1.6μg/mL~102.4μg/mL적농도범위내선성관계량호，평균회수솔위100.75%，RSD위0.82%（n=6）。결론：건립적질량평개방법전속성량호，준학가고，능유효공제농길리감응효제적질량。
Objective:To establish quality standards of monocrotaline gel and conduct preliminary stability test. Methods:Comprehensive evaluation on monocrotaline gel was underwent through content determination ,diadermic test and prelimi-nary stability test. Result:Monocrotaline had good linearity in the range of 1.6 μg/mL~102.4 μg/mL. The average recovery rate was 100.75% and RSD was 0.82%(n=6). Conclusion:The method of quality evaluation established is specific,accu-rate and reliable,and can effectively control the quality of monocrotaline gel.