CAJ | 학술논문

目的：观察地佐辛和舒芬太尼对老年腹腔镜手术患者麻醉苏醒期的影响。方法：选择2012年3月至2012年11月广州市中医医院收治的60例行择期腹腔镜胆囊切除术的老年患者作为研究对象，随机分为D1组、D2组、S组，每组各20例，分别于手术结束前30 min静脉注射地佐辛0.1 mg/kg、0.15 mg/kg和舒苏太尼0.1μg /kg。观察患者自主呼吸恢复时间(T1)、苏醒时间(T2)、拔除气管导管时间(T3)；记录缝合皮肤前、拔除气管导管即时、拔除后1、5、10 min患者收缩压( SBP)、舒张压( DBP)、心率( HR)和Riker镇静躁动评分(SAS 评分)。结果：D1、D2组T1、T3值低于S 组(P<0.05)， D1组T2短于D2组(P<0.05)；D1、D2组SBP、DBP、HR在拔除气管导管即时，拔除后1、5 min比S组低(P<0.05)。结论：与舒芬太尼相比，静脉注射地佐辛0.1 mg/kg用于老年腹腔镜手术患者全身麻醉，麻醉苏醒快，患者血流动力学改变小。
목적：관찰지좌신화서분태니대노년복강경수술환자마취소성기적영향。방법：선택2012년3월지2012년11월엄주시중의의원수치적60례행택기복강경담낭절제술적노년환자작위연구대상，수궤분위D1조、D2조、S조，매조각20례，분별우수술결속전30 min정맥주사지좌신0.1 mg/kg、0.15 mg/kg화서소태니0.1μg /kg。관찰환자자주호흡회복시간(T1)、소성시간(T2)、발제기관도관시간(T3)；기록봉합피부전、발제기관도관즉시、발제후1、5、10 min환자수축압( SBP)、서장압( DBP)、심솔( HR)화Riker진정조동평분(SAS 평분)。결과：D1、D2조T1、T3치저우S 조(P<0.05)， D1조T2단우D2조(P<0.05)；D1、D2조SBP、DBP、HR재발제기관도관즉시，발제후1、5 min비S조저(P<0.05)。결론：여서분태니상비，정맥주사지좌신0.1 mg/kg용우노년복강경수술환자전신마취，마취소성쾌，환자혈류동역학개변소。
Objective:To compare the effects of dezocine and sufentanyl on anesthesia recovery period in elderly patients receiving laparoscopic cholecystectomy. Methods: Sixty elderly patients who underwent laparoscopic cholecystectomy in Guangzhou Hospital of Traditional Chinese Medicine between March 2012 and November 2012 were randomly allocated to be subject to anesthesia induction via intravenous injection of 0. 1 mg/kg dezocine (group D1, n=20), 0. 15 mg/kg dezocin (group D2, n=20) and 0. 1 μg/kg sufentanyl (group S, n=20) at 30 minutes before the end of surgery. The time of spontaneous breathing recovery (T1), awakening (T2) and extubation (T3) was recorded. We also documented the systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and Riker SAS score before suturing the skin, instantaneously after extubation and at minutes 1, 5 and 10 min after extubation. Results:Significantly lower levels of T1 and T3 were noted in groups D1 and D2 (both P<0. 05), but not group S. Group D1 yielded reduced T2 than group D2 (P<0. 05), Groups D1 and D2 were associated with markedly lower levels of SBP, DBP and HR upon extubation and at minutes 1 and 5 after extubation (all P <0. 05). Conclusion:Compared with sufentanyl, intravenous injection with 0. 1 mg/kg dezocine is associated with a shortened duration to recovery and minor changes in hemodynamic in elderly patients who undergo laparoscopic cholecystectomy.